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BLOOD CELL – AN OVERVIEW OF STUDIES IN HEMATOLOGY

BLOOD CELL
Edited by Terry E. Moschandreou .

The editor has incorporated scientific contributions from a diverse group of leading 
researchers in the field of hematology and related blood cell research. This book aims 
to provide an overview of current knowledge pertaining to our understanding of 
hematology. The main subject areas will include blood cell morphology and function, 
the pathophysiology and genetics of hematological disorders and malignancies, blood 
testing and typing, and the processes governing hematopoiesis. Blood cell physiology, 
biochemistry and blood flow are covered in this book. 
This text is designed for hematologists, pathologists and laboratory staff in training and 
in practice. Topics include platelets, whole blood RNA analysis, C-reactive protein, 
pluripotent stem cells, proliferation and differentiation of hematopoietic cells, 
homocysteine in red blood cells metabolism: pharmacological approaches, measurement 
techniques for red blood cells deformability, spontaneous alternation behaviour in 
human neutrophils, microfluidics technology for cell separation, effects of far infrared 
radiation on living body, laboratory reference intervals in Africa, RBC-ATP biochemistry 
and modelling, dynamics of RBC and antigens, transfusion principles, haematological 
and biochemical studies in tigers and ascites syndrome in broiler chickens.
The work presented in this book will be of benefit to medical students and to 
researchers of hematology and blood flow in the microcirculation. This book is written 
primarily for those who have some knowledge of chemistry, biochemistry and general 
hematology. The authors of each section bring a strong clinical emphasis to the book.
I am greatly indebted to many individuals who helped in the preparation of this book. 
Those whom I wish especially to thank for their help with this edition include Drs. Dan 
Goldman and Khoa Nguyen. I am also indebted to Dr. Jiandi Wan, who gave permission 
to use the referenced figure in the chapter contributed by the editor. I also would like to 
thank all those who took the time to email me offering helpful criticisms and 
suggestions. This includes Ms. Sandra Bakic, publishing process manager at InTech.

Dr. Terry E. Moschandreou
University of Western Ontario, Middlesex College,
London, Ontario,
Canada

CONTENTS :

Chapter 1 Platelets 3
Gökhan Cüce and Tahsin Murad Aktan

Chapter 2 Rediscovering Red Blood Cells: Revealing Their Dynamic Antigens Store and Its Role in Health and Disease 13
Mahmoud Rafea and Serhiy Souchelnytskyi

Chapter 3 Homocysteine in Red Blood Cells Metabolism – Pharmacological Approaches 31
Filip Cristiana, Zamosteanu Nina and Albu Elena

Chapter 4 Pluripotent Stem Cells in Bone Marrow and Cord Blood 69
Ambreen Shaikh and Deepa Bhartiya

Chapter 5 C-Reactive Protein 89
Moneer Faraj and Nihaya Salem

Chapter 6 Whole Blood RNA Analysis, Aging and Disease 101
Junko Takahashi, Akiko Takatsu, Masaki Misawa and Hitoshi Iwahashi

Chapter 7 Proliferation and Differentiation of Hematopoietic Cells and Preservation of Immune Functions 119
Osamu Hayashi

Chapter 8 Spontaneous Alternation Behavior in Human Neutrophils 147
Karen A. Selz

Chapter 9 RBC-ATP Theory of Regulation for Tissue Oxygenation-ATP Concentration Model 
Terry E. Moschandreou

Chapter 10 Measurement Techniques for Red Blood Cell Deformability: Recent Advances 167
Youngchan Kim, Kyoohyun Kim and YongKeun Park

Chapter 11 Use of Microfluidic Technology for Cell Separation 195
Hisham Mohamed

Chapter 12 Tigers Blood: Haematological and Biochemical Studies 229
A.B. Shrivastav and K.P. Singh

Chapter 13 Ascites Syndrome in Broiler Chickens – A Physiological Syndrome Affected by Red Blood Cell 243
S. Druyan

Chapter 14 The Effects of the Far-Infrared Ray (FIR) Energy Radiation on Living Body 271
Kikuji Yamashita

Chapter 15 Laboratory Reference Intervals in Africa 303
Clement E. Zeh, Collins O. Odhiambo and Lisa A. Mills

Chapter 16 Principles of Blood Transfusion 321
Nuri Mamak and İsmail Aytekin


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