Open Access Medical Books


Edited by George D. Magel and Stephen Tyring .

In order to fully understand the nature of viruses, it is important to look at them from 
both, their basic science and clinical, standpoints. Our goal with this book was to 
dissect Herpesviridae into its biological properties and clinical significance in order to 
provide a logical, as well as practical, approach to understanding and treating the 
various conditions caused by this unique family of viruses. In addition to their up-todate 
and extensive text, each chapter is laced with a variety of diagrams, tables, charts, 
and images, aimed at helping us achieve our goal. We hope that this book will serve as 
a reference tool for clinicians of various specialties worldwide.
We want to thank the numerous authors from across the world who contributed to 
this book. Herpesviridae - A Look Into This Unique Family of Viruses is a collaboration of 
their experiences, expertise, and research. It truly was an honor and pleasure working 
with them.

George D. Magel, M.D.
Indiana University School of Medicine, Department of Dermatology,
Indianapolis, Indiana

Stephen K. Tyring, M.D., Ph.D.
Department of Dermatology, University of Texas Health Science Center,
Houston, Texas,

Contents :

Chapter 1 Interferon, the Cell Cycle and Herpesvirus 3
H. Costa, S. Correia, R. Nascimento and R.M.E. Parkhouse

Chapter 2 Optimal Gene Expression for Efficient Replication of Herpes Simplex Virus Type 1 (HSV-1) 29
Jun Nakabayashi

Chapter 3 Trojan Horses and Fake Immunity Idols: Molecular Mimicry of Host Immune Mediators by Human Cytomegalovirus 41
Juliet V. Spencer

Chapter 4 Contributions of the EBNA1 Protein of Epstein-Barr Virus Toward B-Cell Immortalization and Lymphomagenesis 65
Amber T. Washington and Ashok Aiyar

Chapter 5 Kaposi’s Sarcoma-Associated Virus Governs Gene Expression Profiles Toward B Cell Transformation 93
Keiji Ueda, Emi Ito, Masato Karayama, Eriko Ohsaki, Kazushi Nakano and Shinya Watanabe

Chapter 6 Human Herpesviruses in Hematologic Diseases 107
Márta Csire and Gábor Mikala

Chapter 7 Zoster-Associated Pain and Post Herpetic Neuralgia 137
Tamara Ursini, Monica Tontodonati, Ennio Polilli, Lucio Pippa and Giustino Parruti

Chapter 8 Varicella Zoster Virus Infection in Pregnancy 173
Irena Narkeviciute and Jolanta Bernatoniene

Chapter 9 KSHV Paracrine Effects on Tumorigenesis 193
Ramona Jochmann, Peter Lorenz, Priya Chudasama, Christian Zietz, Michael Stürzl and Andreas Konrad

Chapter 10 Herpesviruses of Fish, Amphibians and Invertebrates 217
Steven van Beurden and Marc Engelsma

Chapter 11 Nucleoside and Nucleotide Analogues for the Treatment of Herpesvirus Infections: Current Stage and New Prospects in the Field of Acyclic Nucleoside Phosphonates 245
Marcela Krečmerová

Chapter 12 Evidence-Based Treatment of Postherpetic Neuralgia 271
Rafael Galvez and Maria Redondo

Chapter 13 Antiviral Activity of Lactoferrin and Ovotransferrin Derived Peptides Towards Herpesviridae 295
Francesco Giansanti, Loris Leboffe and Giovanni Antonini .

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Published by: Unknown - Tuesday, January 22, 2013


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