Open Access Medical Books


Edited by Humberto Foyaca Sibat .
378 pages . 

Cysticercosis continues to be a gradually increasing health problem affecting millions 
of people all over the world, mainly in developing countries where parasitic zoonoses 
are more common and cysticercosis, as a leading cause, is endemic. Despite 
cysticercosis is a potential eradicable disease, there is epidemiological evidence for an 
increasing prevalence of cysticercosis throughout the world, and evidence of 
increasing morbidity and mortality in many countries as a consequence of higher 
incidence of parasitic zoonotic diseases, migration and globalization. Apart from that,
in some countries of Sub-Saharan Africa, Asia and Latin America, there are 
communities who live, or have lived, either by choice (peoples living in voluntary 
isolation) or by circumstance, without significant contact with globalized civilization, 
therefore their current epidemiological situation is unknown and currently we don’t 
even know how many people are infected by parasites.
At the present moment, there is a significant number of available books on 
cysticercosis. However, we decided to edit this book to introduce novel aspects on 
cysticercosis/neurocysticercosis which were not published before. Therefore, apart 
from the classic issues that cannot be missing in any book about this topic, we 
introduced novel aspects related with cysticercosis and neurocysticercosis as a leading 
cause of epilepsy in developing countries. Of course, the publication of this book could 
not have been possible without the ungrudging efforts put in by a large number of 
individuals working in this field and people from many countries as well as ethnic, 
religious and socioeconomic groups that coincidentally confluence in this publication.
In this book we focus on novel aspects of the historical background of this zoonotic 
parasitic disease, we highlight that T solium infested man long before there was any 
evidence of animal domestication which also served to declare that pigs are not guilty of 
human cysticercosis. We also delivered new hypotheses, and novel clinical descriptions 
and surgical ways of management. Because of the fact that the uncommon clinical 
presentations of cysticercosis and orbital cysticercosis are probably currently 
underestimated, and thus represent an area of legitimate concern, we dedicated two 
chapters these topics. Other chapters written by well known researchers were dedicated 
to the burden of cysticercosis, the control of T solium transmission of taeniosis and 
cysticercosis in endemic countries including the roles of continental networks of 
specialists and of local health authorities. The control of T solium transmission of 
taeniosis and cysticercosis in endemic countries, the roles of continental networks of 
specialists and of local health authorities and the agricultural impact of porcine 
cysticercosis in Africa which were never discussed in previous text book on cysticercosis 
and neurocysticercosis. In this book we also bring all our readers up to date with the 
impact and the latest scientific information in regard to epidemiology of 
neurocysticercosis, clinical diagnoses of neurocysticercosis and epilepsy including our 
experience in Sub-Saharan Africa, extraparenchymal neurocysticercosis addressed to 
health professionals working in the more disadvantage places. Finally we discuss about 
a novel surgical treatment of neurocysticercosis-related epilepsy.
Some chapters and the edition job were entirely made in a rural setting with a lot of 
inconvenience but this edition is aimed at health care professionals including general 
practitioners, family doctors, internists, neurologists, epileptologists, neurosurgeons, 
psychiatrists, medical students, nursing students, and students of the professions 
allied to medicine, among others.
Many abstracts were submitted for review from different parts of the world; about 25 
% were selected for the first phase of this editorial process but unfortunately most of 
abstracts related to neurocysticercosis and written by peoples do not specialized in this 
field were rejected because of lack of basic and novel information. All material for this 
first edition has been thoroughly revised, and updated. Many specialists have 
provided expert advice on changes in their field and their help has been invaluable to 
us in our efforts to keep the relevance of the book for our readership community. All 
chapters were revised again by each author after submission; the final version was
peer-reviewed by experts and recommendations were implemented. Nevertheless, 
some advices of contributors may differ from the approach of the editors or can be 
even different from the medical community. However, we kept and supported it as a 
part of our policy of respecting all scientific criteria, mainly for that work which still 
remains controversial. On the other hand, we also encouraged each author as an 
expert in the field, straight from the beginning to report their personal experience, 
expertise, and results.
Knowing that authors from many countries may have different experience and 
scientific results, in order to achieve a high degree of scientific content with a standard 
level of acceptance, we took a detailed overview of all important novel information.
We all tried to keep the high prestige of our Editorial Company as a main priority and 
we declare our happiness in writing this book in the electronic era with a full-text 
website allowing us to display our scientific messages to an even larger global 
readership, apart from all benefits of print format.
Our aim has been to produce a reference book in which this information would be 
presented in an integrated and rapidly accessible format. With regards to 
pharmacological treatment of cysticercosis/neurocysticercosis we agree that medical 
treatment should be driven by “evidence-based” clinical-imagenologic and serological 
approach, but we did not exclude any “experience-based” approach from expert 
contributors and from the disadvantaged regions.
Every effort has been made to check the drug dosages given in this book. Despite 
dosages from all medication were double checked, it is important for our readership to 
scrutinize last information sheets about new dosages, side-effects, contraindications 
before administering any of the drugs listed. We all attempted to bring in valuable 
updated information about the treatment of cysticercosis/taeniosis/neurocysticercosis 
and other related problems to our readership.

Prof. Humberto Foyaca Sibat
Walter Sisulu University, Mthatha
South Africa


Section 1 Cysticercosis 1

Chapter 1 Introduction to Cysticercosis 
and Its Historical Background 3
Humberto Foyaca Sibat and Lourdes de Fátima Ibañez Valdés

Chapter 2 Neuroimmunoendocrine Interactions in Murine 
Cysticercosis: From the Lab Bench Work to Its Possible Applications in Controlling Porcine Cysticercosis and Human Neurocysticercosis 39
Karen Nava-Castro, Romel Hernández-Bello, Saé Muñiz-Hernández, Lorena López-Griego, Jhonatan A. Hernández-Valdés, Valeria López-Salazar, Nelly Tiempos-Guzmán and Jorge Morales-Montor

Chapter 3 The Burden of Cysticercosis 59
Rachana Bhattarai, Hélène Carabin and Christine Budke

Chapter 4 Agricultural Impact of Porcine 
Cyisticercosis in Africa: A Review 77
Helena A. Ngowi, Samson Mukaratirwa, Faustin P. Lekule, Ndichu Maingi, Charles Waiswa, Chummy Sikasunge, Sonia Afonso, Julienne Sumbu, Sylvia Ramiandrasoa, Mary Louise Penrith and Arve Lee Willingham

Chapter 5 Control of Taenia Solium Transmission 
of Taeniosis and Cysticercosis in Endemic Countries: The Roles of Continental Networks of Specialists and of Local Health Authorities 93
Agnès Fleury, Edda Sciutto, Aline S. de Aluja, Carlos Larralde, Sonia Agudelo, Gisela Maria Garcia, Jaime Fandiño, Randy Guerra, Cáris Nunes, Samuel Carvalho de Aragão, Marcello Sato, Ronaldo Abraham, Arturo Carpio, Franklin Santillan, Maria Milagros Cortez A., Glenda Rojas, Elizabeth Ferrer, Cruz Manuel Aguilar, Juan Carlos Durán and R. Michael E. Parkhouse

Chapter 6 Orbital Cisticercosis. A Challenger 
for Neurologists, Ophthalmologists,
Neuro-Opthalmologists, and General Practitioners 113
Humberto Foyaca Sibat, María Carolina Salazar Campos and Lourdes de Fátima Ibañez Valdés

Chapter 7 What is a Low Frequency of the Disseminated 
Cysticercosis Suggests that Neurocysticercosis is Going to Disappear? 161
Humberto Foyaca Sibat and Lourdes de Fátima Ibañez Valdés

Chapter 8 Uncommon Clinical Manifestations of Cysticercosis 199
Humberto Foyaca Sibat and Lourdes de Fátima Ibañez Valdés

Section 2 Neurocysticercosis 253

Chapter 9 Epidemiology of Neurocysticercosis in Mexico: 
From a Public Health Problem to Its Control 255
Ana Flisser

Chapter 10 Clinical Diagnoses of Neurocysticercosis 277
Arturo Carpio

Chapter 11 Neurocysticercosis and Epilepsy 289
Arturo Carpio

Chapter 12 Epilepsy and Neurocysticercosis in Sub-Saharan Africa 307
Andrea Sylvia Winkler

Chapter 13 Surgical Treatment of 
Neurocysticercosis-Related Epilepsy 341
Alejandro L. Escalaya and Jorge G. Burneo

Chapter 14 Extraparenchymal Neurocysticercosis 349
Kelesidis Theodoros .

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Published by: Unknown - Wednesday, January 30, 2013


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