
Edited by Hossein Babaei .
Hypertension or high blood pressure is widely prevalent and a major risk factor for
cardiovascular diseases including coronary heart disease, myocardial infarction and
stroke, and frequently causes damage to the arterial blood vessels, the eyes and
kidneys. Prolonged hypertension can also lead to enlargement of the heart and may
cause heart failure. This disease is usually asymptomatic until the damaging effects of
hypertension are observed. Therefore, hypertension is known as the "silent killer."
Several survey studies for assessing the burden of hypertension in different societies
revealed that many subjects with hypertension were unaware of their disease, many of
the aware subjects were not on treatment, and many of the treated patients were not
controlled properly, particularly in developing countries. Hypertension afflicts more
than one billion population worldwide and is a leading cause of morbidity and
mortality. It has been predicted that in year 2025 it will increase by 24% in developed
countries and 80% in developing countries. However, the expected increase may be
much higher than these projections.
This book is another contribution to the application of new knowledge in the area of
hypertension. Authors of this book are from different parts of the world sharing their
new knowledge and experience in the direction of deep understanding and more
clarification of the disease. They look from different angles to hypertension, providing
an invaluable resource not only for clinicians, but also for all medical sciences students
and health providers. I hope this book will provide new insight into hypertension
disease and greater visibility and access to detection and treatment of vulnerable
patients.
Prof. Hossein Babaei
Drug Applied Research Center,
School of Pharmacy,
Tabriz University of Medical Sciences,
Iran
CONTENTS :
Chapter 1 New Therapeutics in Hypertension 1
Jorge Luis León Alvarez
Jorge Luis León Alvarez
Chapter 2 Dual L/N-Type Ca2+ Channel Blocker: Cilnidipine as a New Type of Antihypertensive Drug 29
Akira Takahara
Chapter 3 Hypertension and Chronic Kidney Disease: Cause and Consequence – Therapeutic Considerations 45
Elsa Morgado and Pedro Leão Neves
Chapter 4 Potassium-Sparing Diuretics in Hypertension 67
Cristiana Catena, GianLuca Colussi and Leonardo A. Sechi
Chapter 5 Hypertension and Renin-Angiotensin System 85
Roberto de Barros Silva
Chapter 6 Pharmacokinetic Interactions of Antihypertensive Drugs with Citrus Juices 95
Yoshihiro Uesawa
Chapter 7 Drug Interaction Exposures in an Intensive Care Unit: Population Under Antihypertensive Use 121
Érica Freire de Vasconcelos-Pereira, Mônica Cristina Toffoli-Kadri, Leandro dos Santos Maciel Cardinal and Vanessa Terezinha Gubert de Matos
Chapter 8 The Use of Antihypertensive Medicines in Primary Health Care Settings 131
Marc Twagirumukiza, Jan De Maeseneer, Thierry Christiaens, Robert Vander Stichele and Luc Van Bortel
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Published by:
younes younes - Monday, January 21, 2013
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