Open Access Medical Books


Edited by Vishal Madan .

‘Basal Cell Carcinoma’ provides an insight into the recent developments and on going 
research into molecular biology and pathogenesis of basal cell carcinomas. This book 
also includes a chapter on metastatic basal cell carcinoma, an underreported clinical 
entity and sheds light on a custom made mold brachytherapy technique for certain 
basal cell carcinoma subtypes. A detailed account of the genomics of basal cell 
carcinoma compliments other chapters focusing on the pathogenic mechanisms. It is 
hoped that this book will offer the readers a greater understanding of the role of 
cytokines and chemokines and unfold the molecular pathways leading to 
development of basal cell carcinomas. Understanding of such mechanisms is central to 
development of targeted therapy which is of much interest to the clinicians and it is 
hoped that this book will help to facilitate further research into this field.
Dr Vishal Madan MD, MRCP
Consultant Dermatologist, Laser and Dermatological Surgeon
Salford Royal NHS Foundation Trust and Manchester Royal Infirmary,
Stott Lane
Salford, Manchester
M6 8HD

Contents :

Chapter 1 Custom Made Mold Brachytherapy 1
Bahadir Ersu

Chapter 2 Molecularbiology of Basal Cell Carcinoma 19
Eva-Maria Fabricius, Bodo Hoffmeister and Jan-Dirk Raguse

Chapter 3 BCC and the Secret Lives of Patched: Insights from Patched Mouse Models 55
Zhu Juan Li and Chi-chung Hui

Chapter 4 The Role of Cytokines and Chemokines in the Development of Basal Cell Carcinoma .
Eijun Itakura

Chapter 5 Metastatic Basal Cell Carcinoma 79
Anthony Vu and Donald Jr. Laub

Chapter 6 Genomics of Basal and Squamous Cell Carcinomas 93
Venura Samarasinghe, John T. Lear, Vishal Madan

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Published by: Unknown - Tuesday, January 22, 2013

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