Open Access Medical Books

PSORIASIS

PSORIASIS
Edited by Jennifer Soung and Bonnie Koo .
382 pages .

Psoriasis has a worldwide distribution varying according to race and geographic 
location. This book presents the international experience of psoriasis from 
pathophysiology to clinical presentation and treatment strategies.
The first section of the volume focuses on research related to the development of 
therapies for psoriasis. Experimental models and clinical results from immunologically 
directed therapies have demonstrated the important role and interaction of 
inflammatory cytokines, chemokines and immune cells in the pathogenesis of psoriasis. 
The next segment of the volume presents the varying, and often difficult to treat,
clinical manifestations of psoriasis. The role of vitamin D in psoriasis is explored and 
the role of the metabolic syndrome in psoriasis is reviewed.
The final segment of the volume is a discussion of therapy. The review of topical and 
biologic treatments discusses the spectrum of therapies available for psoriasis. The 
efficacy and safety of cyclosporine, a traditional systemic therapy, and the role of diet 
and nutrition is addressed.
We hope you enjoy and find the information useful in your research or practice. We 
urge that you continue to keep abreast of the new developments in psoriasis and share 
your knowledge so that we may advance treatment and cures of psoriasis.
Mona Malakouti (medical student) assisted with editing of the “UVB and Vitamin D 
in Psoriasis”chapter.

Jennifer Soung, M.D.
Assistant Professor & Director
Dermatology Clinical Research
University of California, Irvine
USA

Bonnie Koo, M.D.
Clinical Research Specialist
University of California, Irvine
USA

CONTENTS : 

Part 1 Pathophysiology 1


Chapter 1 Psoriasis and Stem Cells 3 
Kaiming Zhang, Guohua Yin, Xinhua Li,
Xuping Niu, Ruixia Hou, Ruifeng Liu and Junqin Li

Chapter 2 Pathogenesis of Psoriasis: The Role of 
Pro-Inflammatory Cytokines Produced by Keratinocytes 9
Anna Balato, Nicola Balato, Matteo Megna, Maria Schiattarella, Serena Lembo and Fabio Ayala

Chapter 3 Wound Repair Studies Reveal New Insights to Psoriasis 29
Chee Ren Ivan Lam, Ming Jie Tan, Yan Yih Goh,
Mark Boon Yang Tang and Nguan Soon Tan

Chapter 4 Psoriatic Skin Models:
A Need for the Pharmaceutical Industry 47
Jessica Jean, Martha Estrella Garcia-Pérez and Roxane Pouliot

Part 2 Clinical Presentation 63


Chapter 5 Detecting Psoriasis Arthritis Early in the Disease Course – 
Why This is Important and How Dermatologists and Rheumatologists Can Successfully Cooperate? 65
Peter Härle

Chapter 6 Head and Neck Psoriasis 79
Sebastiano Bucolo, Valerio Torre, Giuseppe Romano, Carmelo Quattrocchi, Maura Filidoro and Claudio Caldarelli

Chapter 7 Metabolic Features in Psoriasis 107
Giulia Ganzetti, Anna Campanati, Giulia Liberati and Annamaria Offidani

Chapter 8 UVB and Vitamin D in Psoriasis 121
A. Osmancevic

Chapter 9 Nail Psoriasis 141
Eckart Haneke

Chapter 10 Psoriasis and Stress – 
Psoriasis Aspect of Psychoneuroendocrinology 187
F.Z. Zangeneh, A. Fazeli and F.S. Shooshtary

Chapter 11 Personality in Patients with Psoriasis 209
Ramón Martín-Brufau, Jorge C. Ulnik, Carmen Brufau Redondo and Francisco-Javier Corbalán Berná

Part 3 Treatment 227


Chapter 12 The Role of Immune Response and 
the Impact of Biological Drugs in Psoriasis Patients 229
Amedeo Amedei and Mario Milco D’Elios

Chapter 13 Infliximab Therapy for 
Plaque Psoriasis: The UCL Experience 273
Pierre-Dominique Ghislain

Chapter 14 Systemic Cyclosporin in the Treatment of Psoriasis 287
Delia Colombo and Antonino Di Pietro

Chapter 15 Topical Therapies for Psoriasis 309
Amitava Mitra and Ercem Atillasoy

Chapter 16 Biotech on the Rise: The Treatment of 
Psoriasis with Biological Drugs 331
Daria Capece, Valeria Iansante, Mariafausta Fischietti, Daniela Verzella, Maria Concetta Fargnoli, Ketty Peris, Roberto Giacomelli, Francesca Zazzeroni and Edoardo Alesse

Chapter 17 Food, Nutrition and Diet Therapy in Psoriasis 357
Maria Lucia Diniz Araujo, Paulla Suylane Santos Fernandes Costa and Maria Goretti Pessoa de Araujo Burgos .


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Published by: younes younes - Wednesday, January 30, 2013

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