Open Access Medical Books

TEXTBOOK : BASIC AND CLINICAL ENDOCRINOLOGY UP-TO-DATE

ENDOCRINOLOGY
Edited by Fulya Akin .
360 pages .

This book provides the most up-to-date information on the basic and clinical aspects of 
endocrinology. It offers both researchers and clinicians experts, gold-standard analysis 
of endocrine research and translation into the treatment of diseases such as 
insulinoma, endocrine disease in pregnancy and steroid induced osteoporosis.
Investigates both the endocrine functions of the kidneys and how the kidney acts as a 
target for hormones from other organ systems. 
Presents a uniquely comprehensive look at all aspects of endocrine changes in 
pregnancy and cardiovascular effects of androgens. Clear translational presentations 
by the top endocrinologists in each specific hormone or functional/systems field.
This book contains many important innovations.
I would like to thank our authors who have helped in the preparation of this book. We 
hope it would be useful as an up-to-date resource for endocrinology.
We are particularly grateful for support of our publishers. Their efforts have been 
essential in ensuring the successful publication of this high quality book.
As always, we would like to acknowledge the debt we owe to our families for their 
support during the inevitable periods when’book work’ intruded on family life.

Fulya Akin, M.D.
Pamukkale University Medical School
Denizli/Turkey

CONTENTS :

Part 1 of the textbook : Thyroid Disease 1


Chapter 1 Thyroid Disruptors: How They Act and How We React 3
Natassia Elena Bufalo, Aline Carolina de Nadai da Silva, Raquel Bueno Barbieri, Marjory Alana Marcello, Lucas Leite Cunha, Elaine Cristina Morari and Laura Sterian Ward

Part 2 of the textbook : Pregnancy and Endocrine Disease 35


Chapter 2 Thyroid in Pregnancy 37
Drahomira Springer, Zdenka Limanova and Tomas Zima

Chapter 3 Adrenal Disease and Pregnancy 51
Guadalupe Guijarro de Armas

Part 3 of the textbook : Effects of Androgens 61


Chapter 4 Cardiovascular Effects of Androgens 63
Carlos Wilson, Rodrigo Maass and Manuel Estrada

Chapter 5 Testosterone Therapy and the Heart 79
Güzin Fidan Yaylalı and Yalın Tolga Yaylalı

Chapter 6 Androgens and Vascular Function 91
Mercedes Ferrer

Chapter 7 Orchidectomy Upregulates While Testosterone 
Treatment Downregulates the Expression of Ornithine Aminotransferase Gene in the Mouse Kidney 115
Olivier Levillain, Cyril Dégletagne, Dominique Letexier and Henri Déchaud

Part 4 of the textbook : Insulinomas 133


Chapter 8 Diagnosis and Treatment of Insulinomas in the Adults
D. Vezzosi, A. Bennet, J.C. Maiza, A. Buffet, S. Grunenwald,
J. Fauvel, F. Courbon, P. Otal, N. Carrere and Ph. Caron

Part 5 of the textbook : Aging and Endocrinology 177


Chapter 9 Natural Flavonoids in StAR Gene Expression and 
Testosterone Biosynthesis in Leydig Cell Aging 179
Xing Jia Wang

Chapter 10 Role of Central Insulin-Like Growth Factor-1 Receptor 
Signalling in Ageing and Endocrine Regulation 209
Lorna Moll, Johanna Zemva and Markus Schubert

Part 6 of the textbook : Endocrinology of Stress 261


Chapter 11 The Endocrine Response to Stress - 
A Comparative View 263
Lluis Tort and Mariana Teles

Part 7 of the textbook : Steroid Induced Osteoporosis .


Chapter 12 Genistein Aglycone Demonstrates a Protective and 
Reversible Effect on the Development of Steroid-Induced Secondary Osteoporosis and Increases Bone Breaking Strength in Rats 289
Alessandra Bitto, Francesca Polito, Bruce P. Burnett, Herbert Marini, Robert Levy, Domenica Altavilla and Francesco Squadrito

Part 8 of the textbook : Chronic Renal Disease and Endocrinology 303


Chapter 13 Hormonal Actions and Interactions in Proximal 
Tubule Cells Associated with the Development of Chronic Kidney Disease 305
Akihiko Saito, Michihiro Hosojima and Hiroyoshi Sato

Part 9 of the textbook : Estrogens and Endothelium 321


Chapter 14 Estradiol Regulation of Prostanoids 
Production in Endothelium 323
Susana Novella and Carlos Hermenegildo

Part 10 of the textbook : Factors Affecting Farrowing 339


Chapter 15 Factors Affecting Physiology and 
Endocrinology of Farrowing 341
Olli Peltoniemi and Claudio Oliviero . 


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