Open Access Medical Books


Edited by Ali Gholamrezanezhad . 
816 pages . 

Recently, the field of stem cells and its biological and medical applications has 
attracted a remarkable attention, interest and accordingly funds. These cells are a 
source of great hope for clinical applications in regenerative medicine, for 
pharmaceutical industry and even for genetic studies. There are expanding worldwide 
efforts to discover more about stem cells and to understand how they transform 
into specialized human tissues. The topic is so expanding that every day the scientific 
community is bombarded with information on remarkable advances and 
Although because of diversity and complexity of the topic and also limitations of open 
access publishing, the current book could not cover all aspects of stem cell research, I 
hope that the readers enjoy the book greatly and find it informative, practical and 
educational in the presented discussions. The book was broken to three parts: section 
one as an introduction, section two as an overview on clinical experiences of stem cell 
researches, and section three for the review on some of the recent advances and also 
perspectives in stem cell technology.
I would like to convey my respects and thanks to the authors for their efforts and 
contribution. Collaboration has always been important in academic environment. I am 
very happy to see that the book and chapters are the result of fruitful international 
collaboration involving more than 110 leading scientists and investigators from all 
over the world, from east to west. I hope the stem cell book will encourage continued 
close cooperation and collaboration among its authors.
Best regards,

Ali Gholamrezanezhad, MD, FEBNM
Research Institute for Nuclear Medicine,
Tehran University of Medical Sciences, Tehran, Iran

The Russell H. Morgan Department of Radiology and Radiological Science,
Johns Hopkins University, Baltimore, US

Chapter 1 Stem Cells: General Features and Characteristics 3
Hongxiang Hui, Yongming Tang,Min Hu and Xiaoning Zhao

Chapter 2 Human Cord Blood-Derived Stem Cells 
in Transplantation and Regenerative Medicine 21
Cornel Iancu, Ioana Ilie, Lucian Mocan, Carmen Georgescu, Razvan Ilie, Ileana Duncea, Teodora Mocan, Dana Iancu, and Florin Zaharie

Chapter 3 Mesenchymal Stem Cells: 
Immunology and Therapeutic Benefits 59
Najib El Haddad

Chapter 4 How do Mesenchymal Stem Cells Repair? 83
Patricia Semedo, Marina Burgos-Silva, Cassiano Donizetti-Oliveira and Niels Olsen Saraiva Camara

Chapter 5 Immunogenicity and Immune-Modulating
Properties of Human Stem Cells? 105
Jan Nehlin, Adiba Isa and Torben Barington

Chapter 6 Stem Cell Culture Collection - Promising Strategy 
for Animal Genetic Resource Preservation 145
Weijun Guan, Xiangchen Li, Dapeng Jin, Xiaohong He, Yabin Pu, Qianjun Zhao, Taofeng Lu,
Chunyu Bai, Shen Wu, Xiaohua Su and Yuehui Ma

Chapter 7 The Role of SOX2 in Maintaining Pluripotency and 
Differentiation of Human Embryonic Stem Cells 169
Keiko Adachi, Hirofumi Suemori, Norio Nakatsuji and Eihachiro Kawase

Chapter 8 The Role of MicroRNAs in 
Regulating Cancer Stem Cells 185
Musaffe Tuna and Christopher I. Amos

Part 2 Stem Cells in Clinical Experiences .

Chapter 9 Are We There Yet? 
A Story About Cardiac Stem Cells 213
Shizuka Uchida, Piera De Gaspari and Thomas Braun

Chapter 10 Stem Cell Therapy in Myocardial Infarction 
Clinical Point of View and the Results of the REANIMA Study (REgenerAtion of Myocardium with boNe Marrow Mononuclear Cells in MyocArdial Infarction) 233
Slobodan Obradovic, Bela Balint and Zoran Trifunovic

Chapter 11 Randomized Clinical Trials in Stem Cell Therapy 
for the Heart - Old and New Types of Cells for Cardiovascular Repair 259
Ricardo Sanz-Ruiz, Adolfo Villa Arranz, Enrique Gutiérrez Ibañes, María Eugenia Fernández Santos, Pedro Luis Sánchez Fernández and Francisco Fernández-Avilés

Chapter 12 Autologous Stem Cells for Cardiac 
Repair: New Insights on Clinical Trial Safety and Best Cell Source 283
Nicolas Noiseux, Louis Mathieu Stevens, Jessica Forcillo and Samer Mansour

Chapter 13 Stem Cell Transplantation for the 
Treatment of Peripheral Arterial Disease 325
Nikolaos Papanas

Chapter 14 Myogenic Potential of Murine Embryonic 
Stem Cells in the Dmdmdx Mouse Model for Duchenne Muscular Dystrophy 347
Danielle Ayub-Guerrieri, Poliana C. M. Martins-Machado, Paula C.G. Onofre-Oliveira, Lygia V. Pereira, Camila F. Almeida, Vanessa F. Lopes and Mariz Vainzof

Chapter 15 Stem Cell in Neurological Disorders 363
Nirmeen Kishk and Noha Abokrysha

Chapter 16 Cell Therapy for Parkinson’s Disease: Failure or Success? 401
Magdalena Guerra-Crespo, Alberto K. De la Herrán-Arita, Arturo Hernández-Cruz, José Bargas and René Drucker-Colín

Chapter 17 Stem Cell Therapy for Neuromuscular Diseases 437
Mirella Meregalli, Andrea Farini and Yvan Torrente

Chapter 18 Treatment of the end Stage Liver Cirrhosis by Human Umbilical Cord Blood Stem Cells: Preliminary Results 469
Jong Yoon Bahk, Zhengfu Piao, Jae Hun Jung and Hoon Han

Chapter 19 Stem Cell Therapy for Patients 
with Chronic Liver Disease 501
Reebye, V; Levičar, N and Habib, N.

Chapter 20 Pancreatic Stem Cells: Unresolved Business 513
Fang-Xu Jiang and Grant Morahan

Chapter 21 Cell Sources for Treating Diabetes 533
Subhshri Sahu, Mugdha V. Joglekar, Sundy N. Y. Yang and Anandwardhan A. Hardikar

Chapter 22 Stem Cell Therapy for Islet Regeneration 551
Phuc Pham Van

Chapter 23 Topical Stem and Progenitor Cell Therapy 579
for Diabetic Foot Ulcers Aonghus O’Loughlin and Timothy O’Brien

Chapter 24 Regeneration of the Kidney - Viewed from ES Cell 605
Hirotsugu Iwatani and Enyu Imai

Chapter 25 Periodontal Ligament Stem Cells 619
Hidefumi Maeda, Naohisa Wada, Shinsuke Fujii,
Atsushi Tomokiyo and Akifumi Akamine

Chapter 26 Clinical Stem Cell Imaging and In vivo Tracking 637
Sahar Mirpour and Ali Gholamrezanezhad

Chapter 27 Invasive Fungal Infections in Patients with 
Acute Leukemia and Hematopoietic Stem Cell Transplant Recipients 657
Maxim Norkin and John R. Wingard

Part 3 Perspectives in Stem Cell Technology .

Chapter 28 Synchrotron Radiation and 
Nanotechnology for Stem Cell Research 683
Alessandra Giuliani, Fabrizio Fiori, Adrian Manescu, Vladimir S. Komlev, Chiara Renghini and Franco Rustichelli

Chapter 29 Spontaneous Generation of Neurospheres 
from Mouse Embryonic Stem Cells 709
Roberto Di Maio, Kommu Naga Mohan, Brianna Heath and Leonardo D’Aiuto

Chapter 30 Multidrug Resistance Transporters – 
Roles in maintaining Cancer Stem-Like Cells 719
To, Kenneth K.W. and Fu, L.W.

Chapter 31 Associated Adeno Virus Vector for Producing 
Induced Pluripotent Stem Cells (IPS) for
Human Somatic Cells 747
Edilamar Menezes Oliveira and M Ian Phillips

Chapter 32 Raman Spectroscopy for Noninvasive 
Monitoring of Umbilical Cord Mesenchymal
Stem Cells Viability Transitions 765
P.Chen, F.Zhang, L.Lin, H.Bai, L.Zhang, G.Q.Tang, H.Fang, G.G.Mu, W. Gong, Z. P. Liu, Z. B. Han, H. Zhao and Z. C. Han

Chapter 33 Novel Platforms to Create Labeled Stem Cells 791
Andrew Fontes, Rene Quintanilla and Uma Lakshmipathy . 

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Published by: Unknown - Monday, February 4, 2013


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