Open Access Medical Books

TEXTBOOK : TARGETING NEW PATHWAYS AND CELL DEATH IN BREAST CANCER

BREAST CANCER

Edited by Rebecca L. Aft .

190 pages .
Open Access .


In this book we present manuscripts focusing on mechanisms of breast cancer cell death and new targets for therapeutic intervention by an accomplished group of international investigators. We have divided the book into 2 sections based on these topics. In the first section cell death by autophagy, estrogen induced apoptosis and by immunotherapy will be discussed. In the second section, there is an overview of the DNA damage response and discussion of new targets for intervention. Each of the experts contributing to this book discusses their topic thoughtfully and provides new insight into the topic leading to a new appreciation for these areas of investigation.

Dr. Rebecca L. Aft
Washington University School of Medicine
Department of Surgery
Saint Louis, Missouri
USA

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CONTENTS : 



Part 1 Breast Cancer Cell Death .


 1 Estrogen-Induced Apoptosis in Breast Cancer Cells: Translation to Clinical Relevance 3 Philipp Y. Maximov and V. Craig Jordan

2 Targeted Apoptosis in Breast Cancer Immunotherapy 23 Lin-Tao Jia and An-Gang Yang

 3 Induction of Apoptosis in Human Cancer Cells by Human Eb- or Rainbow Trout Ea4-Peptide of Pro-Insulin-Like Growth Factor-I (Pro-IGF-I) 45 Maria J. Chen, Chun-Mean Lin and Thomas T. Chen

 4 Induction of Autophagic Cell Death by Targeting Bcl-2 as a Novel Therapeutic Strategy in Breast Cancer 57 Bulent Ozpolat, Neslihan Alpay and Gabriel Lopez-Berestein

Part 2 New Anti-Cancer Targets .


 5 The ATF/CREB Family of Transcription Factors in Breast Cancer 71 Jeremy K. Haakenson, Mark Kester and David X. Liu

 6 Newly-Recognized Small Molecule Receptors on Human Breast Cancer Cell Integrin αvβ3 that Affect Tumor Cell Behavior 85 Hung-Yun Lin, Faith B. Davis, Mary K. Luidens, Aleck Hercbergs, Shaker A. Mousa, Dhruba J. Bharali and Paul J. Davis

 7 DNA Damage Response and Breast Cancer: An Overview 97 Leila J. Green and Shiaw-Yih Lin

 8 Cell Cycle Regulatory Proteins in Breast Cancer: Molecular Determinants of Drug Resistance and Targets for Anticancer Therapies 113 Aamir Ahmad, Zhiwei Wang, Raza Ali, Bassam Bitar, Farah T. Logna, Main Y. Maitah, Bin Bao, Shadan Ali, Dejuan Kong, Yiwei Li and Fazlul H. Sarkar

 9 Multidrug Resistence and Breast Cancer 131 Gengyin Zhou and Xiaofang Zhang

 10 Multiple Molecular Targets of Antrodia camphorata: A Suitable Candidate for Breast Cancer Chemoprevention 157 Hsin-Ling Yang, K.J. Senthil Kumar and You-Cheng Hseu .



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