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TEXTBOOK : AMYLOIDOSIS – AN INSIGHT TO DISEASE OF SYSTEMS AND NOVEL THERAPIES

AMYLOIDOSIS

Edited by Işil Adadan Güvenç .

204 pages .
Open Access .


Amyloidosis is a benign, slowly progressive condition characterized by the presence of extracellular fibrillar proteins in various organs and tissues. It has systemic or localized forms. Systemic amyloidosis can involve multiple organs, and shortens life
expectancy, whereas localized amyloidosis usually has a benign course.
Both systemic and localized amyloidosis have been a point of interest for many researchers and there have been a growing number of case reports in the literature for the last decade. The aim of this book is to help the reader become familiar with the presentation, diagnosis and treatment modalities of systemic and localized amyloidosis.
The first and second sections focus on systemic and localized amyloidosis. Each chapter discusses a specific organ or system and is based on review of the literature in English language. The last section consists of three chapters in which novel therapies of amyloidosis are introduced.
I would like to thank all of the authors who have contributed to this book and I believe that this book will provide useful information to physicians and other health professionals practicing in various medical fields.

Işıl ADADAN GÜVENÇ, MD
Department of Otorhinolarygology
Head and Neck Surgery
Başkent University
Zübeyde Hanım Research and Training Hospital
İzmir,
Turkey

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CONTENTS : 




Part 1 Systemic Amyloidosis .


 1 Clinical Presentation of Amyloid A Amyloidosis 3 Nurşen Düzgün

 2 An Overview of the Amyloidosis in Children with Rheumatic Disease 17 Betül Sözeri, Nida Dincel and Sevgi Mir

 3 Intracardiac Thrombosis, Embolism and Anticoagulation Therapy in Patients with Cardiac Amyloidosis – Inspiration from a Case Observation 29 Dali Feng, Kyle Klarich and Jae K. Oh

 4 Cardiovascular Complications in Patients with AL Amyloidosis 53 Maurizio Zangari, Tamara Berno, Fenghuang Zhan, Guido Tricot and Louis Fink

 5 Pulmonary Manifestations of Amyloidosis 63 Mark E. Lund, Priya Bakaya and Jeffrey B. Hoag

 6 Causal or Causal Relationship Between Oral Diseases and Systemic Amyloidosis – From Inflammation to Amyloidosis – A Trouble Connection 77 Murat İnanç Cengiz and Kuddusi Cengiz

 7 Amyloidosis in the Skin 91 Toshiyuki Yamamoto

Part 2 Localized Amyloidosis .


 8 Localized Amyloidosis of the Head and Neck 107 Işil Adadan Güvenç

 9 Localized ENT Amyloidosis – Literature Overview 127 Bouthaina Hammami, Malek Mnejja, Moncef Sellami, Hanene Hadj Taieb, Adel Chakroun, Ilhem Charfeddine and Abdelmonem Ghorbel

10 Oral Localized Amyloidosis 141 Kenji Yamagata and Hiroki Bukawa

Part 3 Novel Aspects in Therapy .


 11 Tocilizumab for the Treatment of AA Amyloidosis 155 Toshio Tanaka, Keisuke Hagihara, Yoshihiro Hishitani and Atsushi Ogata

 12 Cardiac and Multi-Organ Transplantation in Patients with Amyloidosis 171 Eugenia Raichlin and Sudhir S. Kushwaha

 13 Autologous Stem Cell Transplantation in the Treatment of Amyloidosis – Can Manipulation of the Autograft Reduce Treatment-Related Toxicity? 185 Çiğdem Akalin Akkök and Øystein Bruserud






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