Open Access Medical Books



Edited by Puneet Kaur Kochhar .

284 pages . 
Open Access .

Blood transfusions form an integral part of clinical (medical and surgical) practice worldwide. The first well- documented blood transfusion experiment was carried out by the physician Richard Lower (who transfused blood from the cervical artery of a dog into the jugular vein of another dog) in 1667 in Oxford. The earliest experiments of transfusions in human beings were reported from Paris in the same year. Since then, there has been considerable progress in blood transfusion science. Over a century ago, studies of Karl Landsteiner (who described the ABO blood group system), formed the basis of modern hematology. Subsequently, over 250 red cell antigens have been discovered. Despite all this sophisticated knowledge, many aspects of transfusion science still remain an enigma.
Over the last few decades, the knowledge of this immensely complicated blood transfusion science has grown tremendously, and transfusion science has become an increasingly important domain. Simultaneously, we have seen a significant increase in publications, reviews, and textbooks covering scientific knowledge in the subject.
In the recent years, the advanced developments in technology have provided a vast range of sophisticated specialist services (both diagnostic and therapeutic) in modern blood banks. Thus, transfusion medicine has now become a specialist area, encompassing other important fields of medicine such as hematology, immunology, microbiology, etc.
This book is not an exhaustive textbook on the subject of blood transfusion; instead it discusses various aspects of transfusion medicine in clinical practice (including role of ABO blood group system, transfusion practices in various systemic surgeries such as orthopedics, cardiac surgery, obstetrics, etc., and alternatives available to reduce allogenic blood transfusions, brief discussion of transfusion related infections and lastly the role of transfusion in immunomodulation) in different chapters. Thus, this book is an endeavor to provide the readers a comprehensive text on the subject of transfusion medicine in clinical practice.

I am thankful to my colleagues who have contributed to this book and to the publishing process manager, Ms. Irena Voric, who has worked for the compilation of this book with utmost dedication.

Dr. Puneet Kaur Kochhar
Department of Obstetrics and Gynecology,
Lok Nayak Hospital, New Delhi,



Part 1 ABO in the Context Blood Transfusion .

 1 ABO in the Context of Blood Transfusion and Beyond 3 Emili Cid, Sandra de la Fuente, Miyako Yamamoto and Fumiichiro Yamamoto

Part 2 Blood Transfusion in Medicine and Surgery .

 2 Blood Transfusion Therapy in High Risk Surgical Patients 25 João Manoel Silva Junior and Alberto Mendonça P. Ferreira

 3 Blood Transfusion Practices in Major Orthopaedic Surgery 35 Saqeb B. Mirza, Sukhmeet S. Panesar and Douglas G. Dunlop

 4 Transfusion Reduction in Orthopedic Surgery 61 Ruud H.G.P. van Erve and Alexander C. Wiekenkamp

 5 Scope of Blood Transfusion in Obstetrics 83 Subhayu Bandyopadhyay

 6 Uterine Atony: Management Strategies 97 Pei Shan Lim, Mohamad Nasir Shafiee, Nirmala Chandralega Kampan, Aqmar Suraya Sulaiman, Nur Azurah Abdul Ghani, NorAzlin Mohamed Ismail, Choon Yee Lee, Mohd Hashim Omar and Muhammad Abdul Jamil Mohammad Yassin

 7 Effects of Blood Transfusion on Retinopathy of Prematurity 129 Ebrahim Mikaniki, Mohammad Mikaniki and Amir Hosein Shirzadian

Part 3 Preventing Transfusion Transmitted Infections .

 8 Transfusion-Transmitted Bacterial, Viral and Protozoal Infections 143 Pankaj Abrol and Harbans Lal

 9 Implicating the Need for Serological Testing of Borna Disease Virus and Dengue Virus During Blood Transfusion 155 S. Gowri Sankar and A. Alwin Prem Anand

 10 Human T-Lymphotropic Viruses (HTLV) 175 Marina Lobato Martins, Rafaela Gomes Andrade, Bernardo Hinkelmann Nédir and Edel Figueiredo Barbosa-Stancioli

Part 4 Alternative Strategies to Allogenic Blood Transfusion .

 11 Bloodless Medicine and Surgery 191 Nathaniel I. Usoro

 12 Autotransfusion: Therapeutic Principles, Efficacy and Risks 205 A.W.M.M. Koopman-van Gemert

 13 Impact of Acute Normovolemic Hemodilution in Organ and Cell Structure 223 D.A. Otsuki, D.T. Fantoni and J.O.C. Auler Junior

 14 Cryopreservation of Blood 233 Miloš Bohoněk

Part 5 Immunomodulatory Effects of Blood Transfusion .

 15 Effect of Blood Transfusion on Subsequent Organ Transplantation 245 Puneet K. Kochhar, Pranay Ghosh and Rupinder Singh Kochhar

 16 Posthepatic Manipulative Blood Extraction with Blood Transfusion Alleviates Liver Transplant Ischemia/Reperfusion Injury and Its Induced Lung Injury 255 Changku Jia

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Published by: Unknown - Monday, May 6, 2013


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