Open Access Medical Books



Edited by Letícia Rangel .

628 pages .
Open Access .

Notwithstanding the advances in the cancer research field, the related epidemiology data remain dramatic and clearly point to an urge to optimize and innovate the therapeutic approaches to fight cancer. Indeed, the elucidation of important aspects of cancer biology and human tumorigenesis has progressively enabled oncologists to provide more accurate cancer diagnosis; thus, guiding more efficiently the treatment of multiple cancer types and subtypes.
Nonetheless, cancer treatment still challenges researchers and clinicians, as proven by the still impressive and increasing number of worldwide cancer-related deaths, caused either by the disease late diagnosis, surgical limitations or radio/chemoresistance. Adding complexity to the inter-individual variables, cancer comprises multiple diseases harboring diverse genetic and epigenetic signatures, which types and subtypes respond differentially to treatment, and are associated to distinct clinical outcomes.
Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections:
i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches;
ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer;
iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling.
Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.

Prof. Letícia Rangel
Federal University of Espírito Santo, Brazil



Section 1 Cancer Treatment: Conventional and Innovative Pharmacological Approaches .

 1 Conventional Cancer Treatment 3 Isabella dos Santos Guimarães*, Renata Dalmaschio Daltoé*, Alice Laschuk Herlinger, Klesia Pirola Madeira, Taciane Ladislau, Iuri Cordeiro Valadão, Paulo Cilas Morais Lyra Junior, Sarah Fernandes Teixeira, Gustavo Modesto Amorim, Diandra Zipinotti dos Santos, Karina Rangel Demuth and Leticia Batista Azevedo Rangel

 2 Target Cancer Therapy 37 Taciane Ladislau, Klesia P Madeira, Renata D Daltoé, Isabella S Guimarães, Sarah F Teixeira, Paulo CM Lyra-Júnior, Iuri C Valadão, Leticia BA Rangel and Alice L Herlinger

 3 Anticancer Properties of Cardiac Glycosides 65 Varisa Pongrakhananon

 4 Liposomes as Carriers of Anticancer Drugs 85 Sávia Caldeira de Araújo Lopes, Cristiane dos Santos Giuberti, Talita Guieiro Ribeiro Rocha, Diêgo dos Santos Ferreira, Elaine Amaral Leite and Mônica Cristina Oliveira

Section 2 Combinatorial Strategies to Fight Cancer: Surgery, Radiotherpay, Backytherapy, Chemotherapy, and Hyperthermia .

 5 The Role of Surgery in the Treatment of Hepatocellular Carcinoma 127 Georgios Tsoulfas and Polyxeni Agorastou

 6 Laparoscopic Surgery in Genitourinary Cancer Treatment 147 March Villalba José Antonio

 7 Current Strategies in the Management of Adenocarcinoma of the Rectum 163 Sergio Huerta and Sean P. Dineen

 8 Mesothelioma: An Evidence-Based Review 177 Julie Goudreault and Anne Dagnault

 9 Definitive Chemo-Radiotherapy for Resectable Esophageal Cancer — Unresolved Problems Remain 201 Shouji Shimoyama

 10 A Review of Radiation Therapy’s Role in Early-Stage Breast Cancer and an Introduction to Electronic Brachytherapy 223 Brent Herron, Alex Herron, Kathryn Howell, Daniel Chin and Luann Roads

 11 Radiosurgery and Hypofractionated Stereotactic Irradiation with Photons or Protons for Tumours of the Skull Base 239 Dante Amelio, Marco Cianchetti, Barbara Rombi, Sabina Vennarini, Francesco Dionisi, Maurizio Amichetti and Giuseppe Minniti

 12 Hyperthermia: Cancer Treatment and Beyond 257 Ahmed Bettaieb, Paulina K. Wrzal and Diana A. Averill-Bates

 13 Glioblastomas, Astrocytomas: Survival Amelioration Adding Hyperthermia to Conformal Radiotherapy and Temozolomide — Use of Pegylated Doxorubicin and Hyperthermia in the Treatment of a Recurrent Case 285 Gianfranco Baronzio, Gurdev Parmar, Michela De Santis and Alberto Gramaglia

Section 3 The Immunotherapy of Cancer .

 14 Targeted Cancer Therapy by Dendritic Cell Vaccine 299 Hiroyuki Abe, Touko Shimamoto, Shinichiro Akiyama and Minako Abe

 15 Immunotherapy of Urinary Bladder Carcinoma: BCG and Beyond 319 Yi Luo, Eric J. Askeland, Mark R. Newton, Jonathan R. Henning and Michael A. O’Donnell

 16 Anti-Angiogenic Active Immunotherapy for Cancers: Dawn of a New Era? 363 Jianping Pan and Lihuang Zhang

Section 4 Multidisciplinarity in Cancer Therapy: Nutrition and Beyond .

 17 Nutrigenomics and Cancer Prevention 391 Júlio César Nepomuceno

 18 The Impact of Vitamin D in Cancer 417 Khanh vinh quốc Lương and Lan Thi Hoàng Nguyễn

 19 The Treatment of Cancer: A Comprehensive Therapeutic Model Entailing a Complex of Interaction Modalities 455 R. Saggini and M. Calvani

Section 5 Supportive Care for Cancer Patients .

 20 Supportive and Palliative Care in Solid Cancer Patients 487 Bassam Abdul Rasool Hassan, Zuraidah Binti Mohd Yusoff, Mohamed Azmi Hassali and Saad Bin Othman

 21 Impact of Cancer Treatment on Reproductive Health and Options for Fertility Preservation 519 Kenny A. Rodriguez-Wallberg

Section 6 Perspectives in Cancer Biology and Modeling .

 22 Sialyl Salivary–Type Amylase Associated with Ovarian Cancer 541 Takanori Moriyama

 23 Role of CREB Protein Family Members in Human Haematological Malignancies 555 Francesca D’Auria and Roberta Di Pietro

 24 Life-Cycling of Cancer: New Concept 583 Marina Shaduri and Marc Bouchouchaq

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Published by: Unknown - Sunday, May 12, 2013


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