Open Access Medical Books



Edited by Mart Min .

206 pages .
Open Access .

The use of artificial pacing has a marvellous history – clinical applications of cardiac pacing are known since 1958, when Earl Bakken, a cofounder of the company Medtronic in Minneapolis, USA, designed and produced a wearable electronic pacemaker for a patient of Dr. C. Walton Lillehei, a pioneer in open heart surgery. In October 1958, the first cardiac pacemaker was implanted at the Karolinska Institute in Solna near Stockholm, Sweden, by surgeon Dr. Åke Senning. This transistorized and battery powered pacemaker was designed by Rune Elmqvist and manufactured in Siemens-Elema, a predecessor of today's St. Jude Medical Sweden AB. Availability of miniaturized cardiac pacemakers was connected with emerging of the era of silicon based electronics – first transistors, then integrated circuits.
Nowadays pacemakers are complicated electronic devices, containing, besides a multiple-output generator of electrical pulses, sensing and computing units together with control and communication components for achieving the well-functioning demand-responsive pacing. Installed batteries can ensure about 10-years power supply. Dual-chamber synchronized pacing of both, right atrium and right ventricle, is already in common clinical use. Moreover, left ventricle pacing in cardiac synchronization therapy (CRT) is also introduced and used clinically in different ways and modes.
Further development of pacemakers as electronic devices will not stop in the near future, but this is not a straightforward subject of this book.
In Section 1, an alternative, biological way for development of so called biologic pacemakers on the bases of tissue engineering and studying the physiological processes taking place in living cell cultures is discussed. Self synchronization of myocites’ activities is the most interesting aspect of these studies.
However, effective and safe use of versatile opportunities of modern pacemakers and pacing modes in different clinical situations requires outstandingly smart medical treatment on the bases of studying a great number of clinical cases. An important problem to be solved is the most resultant placing of pacing electrodes. Analyses of own experiences and the trials of colleagues, drawing conclusions and giving practical advices for different clinical tasks is a highly valuable contribution of authors in the Section 2.

Though the professional medical society has a long term experience with implementation of pacemakers, unexpected complexities and even complications in new clinical situations may arise. The authors of chapters in Section 3 analyse the cases they have met in their own or colleagues’ practice and warn about possible complications. These aspects can maybe even be acknowledged as the most valuable contributions to this book.
The book discusses practical experiences on implementation of modern pacemakers and different cardiac pacing methods in various clinical indications. A forehanded glance on the ways of further development in cardiac pacing methods and means is also presented. The approach to different clinical problems that is more pragmatic than usual, makes this book valuable for wide range of readers amongst medical professionals and biomedical engineers.

Prof. Mart Min, PhD
Thomas Johann Seebeck Department of Electronics
Tallinn University of Technology



Part 1 Biological Aspects of Cardiac Pacing .

 1 Biologic Pacemaker - Role of Gene and Cell Therapy in Cardiac Arrhythmias 3 Hadi A.R. Hadi Khafaji

 2 Coherent Resonant Properties of Cardiac Cells 25 A. Chorvatova and D. Chorvat Jr

Part 2 Pacemakers in Clinical Practice .

 3 Clinical Applications of Pacemakers in Patients with Bradycardia and Other Specific Conditions 47 Guillermo Llamas-Esperón, Vitelio Mariona, Santiago Sandoval-Navarrete and Rocío Muñoz-Sandoval

 4 Permanent Cardiac Pacing in Adults with High Grade Atriovetricular Block and Preserved Left Ventricular Function: Optimal Mode and Site of Pacing 73 Ouali Sana

 5 Cardiac Resynchronization Therapy: Lead Positioning and Technical Advances 97 Karl Mischke and Christian Knackstedt

 6 Implantable Loop Recorder in Clinical Practice 113 Dominique Babuty, Bertrand Pierre, Nicolas Clémenty, Bénédicte Lallemand, Olivier Marie and Laurent Fauchier

Part 3 Complexities and Possible Complications .

 7 Pacemaker Following Adult Cardiac Surgery 135 Silvero Miriam, Browne Leonardo and Solari Gabriel

 8 Early Complications After Pacemaker Implantations 161 Kabayadondo Maidei Gugu and de Meester Antoine

 9 Lead Extraction in Congenital Heart Disease Patients – Indications, Technique and Experience 181 Philip Chang, Miguel Salazar, Michael Cao and David Cesario

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Published by: Unknown - Monday, May 13, 2013


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