Open Access Medical Books


Edited by Manisha Sahay .
Open Access . 
236 pages .

The first section deals with chronic kidney disease (CKD). CKD is assuming epidemic proportions. Metabolic bone disease is an important complication of CKD. Parathormone is an important uremic toxin and plays an important role in the pathogenesis of renal osteodystrophy and vascular calcification in chronic kidney disease. The role of elevated calcium and phosphorus product in the genesis of mineral bone disease is discussed. The presence of kidney disease, manifested by low glomerular filtration rates (GFR) and/or large amounts of protein in the urine, is independently associated with increased rates of cardiovascular disease (CVD). The severity of kidney disease is associated with graded increases in the risk of CVD and death. This is described in the chapter on cardiovascular diseases in CKD. Chronic kidney disease affects not only physical but also psychological health and well-being; this is highlighted in the chapter on social and psychological aspects of chronic kidney disease. Prevention of chronic kidney disease is the only solution to stem the increasing prevalence of CKD globally and hence emphasis should be on evolving screening methods for early detection, as is discussed in the chapter on screening for chronic kidney disease. The role of renin angiotensin system in the progression of renal diseases is stressed. The second section of the book includes chapters on renal transplantation that will be of use to the readers. I am sure this book will be a valuable addition to the reader’s library.

Dr. Manisha Sahay
Department of Nephrology
Osmania General Hospital & Osmania Medical College



Part 1 Chronic Kidney Disease .

 1 Screening for Chronic Kidney Disease 3 
Ross Francis and David Johnson

 2 The Role of Renin Angiotensin System Inhibitors in Renal Protection: Lessons from Clinical Trials 17 Ljuba Stojiljkovic

 3 Parathyroid Hormone-Related Protein as a Mediator of Renal Damage: New Evidence from Experimental as well as Human Nephropathies 31 Ricardo J. Bosch, María Isabel Arenas, Montserrat Romero, Nuria Olea, Adriana Izquierdo, Arantxa Ortega, Esperanza Vélez, Jordi Bover, Juan C. Ardura and Pedro Esbrit

 4 Psychological and Social Aspects of Living with Chronic Kidney Disease 47 Daphne L. Jansen, Mieke Rijken, Monique J.W.M. Heijmans, Ad A. Kaptein and Peter P. Groenewegen

 5 Role of Fermentable Carbohydrate Supplements in the Course of Uremia 75 Hassan Younes

 6 Phosphorus and Calcium Metabolism Disorders Associated with Chronic Kidney Disease Stage III-IV (Systematic Review and Meta-Analysis) 95 L. Milovanova, Y. Milovanov and A. Plotnikova

 7 Recent Trials in Hypertension 119 Samra Abouchacra and Hormaz Dastoor

 8 Cardiac Biomarkers in End-Stage Renal Disease 147 Leo Jacobs, Alma Mingels and Marja van Dieijen-Visser

 9 Cardiovascular Complications in Renal Diseases 161 Mohsen Kerkeni

Part 2 Renal Transplantation .

 10 Laparoscopic Transperitoneal and Retroperitoneal Nephrectomies in Children: A Change of Practice 170 Julio J. Báez, Gaston F. Mesples and Alfredo E. Benito

 11 Mechanisms of Calcineurin Inhibitor Nephrotoxicity in Chronic Allograft Injury 191 Craig Slattery, Hilary Cassidy, Olwyn Johnston, Michael P. Ryan and Tara McMorrow

 12 Malignancy Following Renal Transplantation 213 A. Vanacker and B. Maes

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Published by: Unknown - Wednesday, May 22, 2013


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