Open Access Medical Books



Edited by Branislav Baškot .

426 pages .
Open Access .

This book brings together contributions from around the world, investigators who are clinical versus imaging science in their orientation, and representatives from academic medical centers and the imaging industry. Each article is written to be accessible to those with a basic knowledge of coronary imaging but also to be stimulating and educational to those who are experts and investigators in medical imaging.
This book covers where advances have been dramatic in the past two decades and shows the major contributions of the imaging scientists and engineers from both academia and industry. Patients with know or suspected coronary artery disease who are asymptomatic or who have stable symptoms are often evaluated noninvasive.
Functional test, such as stress electrocardiography, stress echocardiography, and stress nuclear perfusion imaging, detect and quantity the presence of ischemia based on electrical, mechanical, or perfusion abnormalities, indirectly, but nuclear perfusion imaging directly, establishing the burden of coronary artery disease. Multidetector CT (MDCT) has emerged as a tool to evaluate noninvasive the coronary anatomy. MDCT has overcome many of its original limitations and now provides ECG-gated acquisition with short acquisition time, sub millimeter spatial resolution, allowing excellent visualization of the coronary arteries. Over the last 15 years, the rate of technologic advancements leading to improved coronary angiography with MDCT has rapidly exceeded those of other cardiac imaging modalities. Image quality is undergoing constant refinement, and the number of uninterpretable coronary studies has gradually decreased from 20%-40% using for detector, to 15% - 25% with 16- detector, and is now as low as 3% to 10% with 64-detector systems.
But this section is also devoted to the current state of myocardial perfusion imaging (MPI). MPI is well establishment imaging techniques and is already integral part of the management of coronary artery disease (CAD), and is included in a number of professional guidelines. Coronary angiography, considered the “gold standard” for the diagnosis of CAD, often does not provide information about the functional significance of coronary stenosis, especially in borderline lesions. Andres Gruentzig said; when coronary angiography founded coronary narrowing, I would like to have some kind of diagnostic procedure who gives me functional significance that lesion. MPI is very important diagnostic tool for the diagnosis culprit lesions, and indicating who patients have for cardiovascular intervention (PCI or ACBP). The predominant theme is that MPI finding can serve as the gatekeeper for more costly and more risky invasive strategies in the evaluation and treatment of patients with coronary artery disease.

The book Coronary Angiography – Advances in Noninvasive Imaging Approach for Evaluation of Coronary Artery Disease includes a series of articles that provide a stateof‐ the‐art summary of the current clinical applications of cardiac CT, reviews data that support the accuracy and the prognostic use of CT coronary angiography and reports of the newest technological advances and promising future applications of these imaging modalities. Its also provide other diagnostic approach like functional test, which finding helps to make decision about invasive strategies with best benefit for patients.
Finally, the next decades should see even greater advances in the field, and such breakthroughs will be instrumental in further enhancing the information that can be derived from functional testing for the assessment of myocardial blood flow, cardiac function, and myocardial viability. Readers of Coronary Angiography will enjoy in this book and will find the information and expert opinions very useful to their clinical practice.

Branislav Baškot MD PhD Ass Prof
Department of Nuclear Medicine Imaging “Dr Baskot”



 1 Utilization of Functional Tests Prior to and Adherence to Guidelines on Coronary Angiography 1 James T Leung and Dominic Y Leung

 2 Transthoracic Echocardiography in the Assessment of Coronary Arteries 21 Alla Boshchenko, Alexander Vrublevsky and Rostislav Karpov

 3 Contrast Echocardiography in Coronary Artery Disease 61 Mai Tone Lønnebakken and Eva Gerdts

 4 Non-Invasive Imaging in Approaching Ischemic Coronary Artery Disease 81 Lucia Agoston-Coldea, Teodora Mocan and Silvia Lupu

 5 Non-Invasive Coronary Angiography 99 Mohanaluxmi Sriharan, Paula McParland, Stephen Harden and Edward Nicol

 6 Coronary CT Angiography as an Alternative to Invasive Coronary Angiography 123 Seshu C. Rao and Randall C. Thompson

 7 New Noninvasive Modalities in Coronary Angiography: Cardiac Computed Tomography Angiography 141 Ryotaro Wake and Minoru Yoshiyama

 8 Simultaneous Assessment Beyond Coronary Stenosis by Multislice Computed Tomography 151 Shoichi Ehara and Kenei Shimada

 9 Assessment of Coronary Artery Bypass Graft (CABG) Patency and Graft Disease Using Multidetector Computed Tomography (MDCT) 161 Bong Gun Song, Hyun Suk Yang, Joon Hyung Doh, Hong Jang, Gu Hyun Kang, Yong Hwan Park, Woo Jung Chun, Ju Hyeon Oh, Sung Min Ko and Hweung Kon Hwang

 10 Detection Myocardial Bridging Using Non-Invasive Technique 183 Junbo Ge and Jianying Ma

 11 When Cardiac Computed Tomography Becomes the Gold Standard Technique to Evaluate Coronary Artery Disease Patients 199 Mohamed Bamoshmoosh

 12 Physiologic Risk Assessment in Stable Ischemic Heart Disease – Functional Evaluation Versus Coronary Anatomy 215 Alessia Gimelli and Paolo Marzullo

 13 Clinical Significance of Tetrofosm in Extracardiac Uptake During Myocardial Perfusion Imaging 225 Panagiotis Georgoulias, Varvara Valotassiou, Ioannis Tsougos, George Angelidis and Nikolaos Demakopoulos

 14 Myocardial Perfusion Imaging in Diagnosis of Culprit Lesion in Patients Undergoing Elective Percutaneous Coronary Intervention 249 Branislav Baskot, Slobodan Obradovic, Saso Rafajlovski, Branko Gligic, Robert Jung, Vladimir Ivanovic, Miroslav Bikicki and Miodrag Pavlovic

 15 New Noninvasive Modalities in Coronary Angiography - Diagnostic Values of New Biomarkers for Cardiovascular Disease 267 Yilmaz. N, Yegin A and Aykal G.

 16 The Role of Inflammatory Biomarkers in the Assessment of Coronary Artery Disease 281 Patrícia Napoleão, Mafalda Selas, Cláudia Freixo, Catarina Ramos, Valeska Andreozzi, Antónia Turkman, Miguel Mota Carmo, Ana Maria Viegas-Crespo, Rui Cruz Ferreira and Teresa Pinheiro

 17 Platelet, Fatty Acids, Membrane Viscosity, Depression and Ischemic Heart Disease - Biological-Molecular Path, with Medical-Anthropology Insights 315 Massimo Cocchi, Lucio Tonello and Fabio Gabrielli

 18 Acceleration of New Biomarkers Development and Discovery in Synergistic Diagnostics of Coronary Artery Disease 353 Ewa Stępień

 19 Biomarkers and Coronary Atherosclerotic Burden and Activity as Assessed by Coronary Angiography and Intra-Coronary Imaging Modalities 375 Valentina Loria, Nicola Cosentino, Rocco A Montone and Giampaolo Niccoli

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Published by: Unknown - Monday, May 6, 2013


  1. My absolute favorite class I've ever taken is anatomy. I think the human body is fascinating in every way. I actually got to job shadow a surgeon while he was performing a heart surgery. I think they had done a coronary angiography previously and that's how they found out that patient needed to have heart surgery in the first place.
    Shelly Slader |