Open Access Medical Books

TEXTBOOK : ETIOLOGY, PATHOGENESIS AND PATHOPHYSIOLOGY OF AORTIC ANEURYSMS AND ANEURYSM RUPTURE

ANEURYSM RUPTURE

Edited by Reinhart T. Grundmann .

Open Access .
232 pages .


This book considers mainly etiology, pathogenesis, and pathophysiology of aortic aneurysms (AA) and aneurysm rupture and addresses anyone engaged in treatment and prevention of AA. Multiple factors are implicated in AA pathogenesis, and are outlined here in detail by a team of specialist researchers. Initial pathological events in AA involve recruitment and infiltration of leukocytes into the aortic adventitia and media, which are associated with the production of inflammatory cytokines, chemokine, and reactive oxygen species. AA development is characterized by elastin fragmentation. As the aorta dilates due to loss of elastin and attenuation of the media, the arterial wall thickens as a result of remodeling. Collagen synthesis increases during the early stages of aneurysm formation, suggesting a repair process, but resulting in a less distensible vessel. Proteases identified in excess in AA and other aortic diseases include matrix metalloproteinases (MMPs), cathepsins, chymase and others. The elucidation of these issues will identify new targets for prophylactic and therapeutic intervention.

Prof. Dr. Reinhart T. Grundmann
Medical Expert
Burghausen
Germany

-->

CONTENTS OF THE TEXTBOOK : 




 1 Etiology and Pathogenesis of Aortic Aneurysms 1 Carl W. Kotze and Islam G. Ahmed

 2 Matrix Metalloproteinases in Aortic Aneurysm – Executors or Executioners? 25 Tomasz Grzela, Barbara Bikowska and Małgorzata Litwiniuk

 3 Mast Cell Density and Distribution in Human Abdominal Aortic Aneurysm 55 Sumiharu Sakamoto, Toshihiro Tsuruda, Kinta Hatakeyama, Yoko Sekita, Johji Kato, Takuroh Imamura, Yujiro Asada and Kazuo Kitamura

 4 The Role of Complement in the Pathogenesis of Artery Aneurysms 67 Fengming Liu, Annie Qin, Lining Zhang and Xuebin Qin

 5 Immunoglobulin G4-Related Inflammatory Aortic Aneurysm 91 Mitsuaki Ishida and Hidetoshi Okabe

 6 Transcriptomic and Proteomic Profiles of Vascular Cells Involved in Human Abdominal Aortic Aneurysm 105 Florence Pinet, Nicolas Lamblin, Philippe Ratajczak, David Hot, Emilie Dubois, Maggy Chwastyniak, Olivia Beseme, Hervé Drobecq, Yves Lemoine, Mohammad Koussa and Philippe Amouyel

 7 Multifaceted Role of Angiotensin II in Vascular Inflammation and Aortic Aneurysmal Disease 119 Xiaoxi Ju, Ronald G. Tilton and Allan R. Brasier

 8 Aortitis and Aortic Aneurysm in Systemic Vasculitis 137 Ana García-Martínez, Sergio Prieto-González, Pedro Arguis, Georgina Espígol, José Hernández-Rodríguez and Maria C Cid

 9 Drug-Induced Aortic Aneurysms, Ruptures and Dissections 159 Olav Spigset

 10 Pathophysiology of Abdominal Aortic Aneurysm Rupture and Expansion: New Insight on an Old Problem 175 Efstratios Georgakarakos and Christos V. Ioannou

 11 An Analysis of Blood Flow Dynamics in AAA 191 Bernad I. Sandor, Bernad S. Elena, Barbat Tiberiu, Brisan Cosmin and Albulescu Vlad

 12 Numerical Simulation in Aortic Arch Aneurysm 207 Feng Gao, Aike Qiao and Teruo Matsuzawa .





You've just read an article category Cardiology and Cardiovascular / Pathology by title TEXTBOOK : ETIOLOGY, PATHOGENESIS AND PATHOPHYSIOLOGY OF AORTIC ANEURYSMS AND ANEURYSM RUPTURE. You can bookmark this page URL http://www.openaccessbooks.com/2013/05/TEXTBOOK-ETIOLOGY-PATHOGENESIS-PATHOPHYSIOLOGY-AORTIC-ANEURYSMS-ANEURYSM-RUPTURE.html. Thank you!
Published by: younes younes - Friday, May 17, 2013

No comments yet "TEXTBOOK : ETIOLOGY, PATHOGENESIS AND PATHOPHYSIOLOGY OF AORTIC ANEURYSMS AND ANEURYSM RUPTURE"

Post a Comment