Open Access Medical Books



Edited by Marek L. Kowalski .

Open Access .
226 pages .

During the last decades, an increasing prevalence of allergic diseases has been observed all over the world. According to recent estimates from the Global Allergy And Asthma European Network (GA2LEN), more than 50% of the European population will suffer from allergies by 2020. Allergic rhinitis is one of the most common allergic disorders affecting 20-40% of the population at all ages and the prevalence of the disease tends to increase all over the world. Allergic rhinitis adversely affects emotional well-being and social functions. It impairs cognitive functions and decreases the quality of life of patients . In children it is one of the most common causes of absence from school and, if untreated, may result in poorer learning ability.
Allergic rhinitis, while troublesome for a patient , may also be a challenge for the physician. Despite the progress in prevention, anti-inflammatory treatment and allergen- specific treatments (for example specific immunotherapy) a significant proportion of patients still suffer from serious symptoms of allergic rhinitis. That is why physicians must still learn more about the pathophysiology of the disease and why physicians and patients are looking forward for novel diagnostic and therapeutic approaches.
Allergic rhinitis may predispose to chronic sinusitis or otitis media and is associated with an increased risk of asthma. The fact that allergic rhinitis is not just a local disease, but is a manifestation of systemic allergy, has been appreciated by the doctor for a long time. In 1928 the Californian physician HP Merril concluded that allergic rhinitis ”…is not a disease entity, but a local manifestation of a general hypersensitiveness to irritants, generally proteins, but probably to other substances as well. It is often accompanied by other types of allergic reaction, such as asthma, and like such must be considered as a symptom and not as a disease”. Since that time the systemic nature of allergic rhinitis has been well documented and the concept of oneairway disease led to development of an ARIA document advocating a systemic approach to the management of allergic rhinits.
The chapters of this volume address a variety of important topics related to allergic rhinitis . They begin with a description of innovative translational approaches allowing for the unification of animal and human models. Contributing authors provide up-to-date reviews of clinical aspects of allergic rhinitis in children, its association with bronchial asthma and other co-morbid conditions. They also discuss the impact of allergic rhinitis on sleep and sports. Together with articles on diagnostic approaches as well as novel treatments, this book offers a comprehensive and stimulating review of the topic.
May this book find a wide readership among allergists and other physicians interested in allergic disease, and also among pediatricians, general practitioners and other specialists who increasingly have to deal with this seemingly benign, but sometimes extremely troublesome, disease.

Professor Marek L. Kowalski, M.D., Ph.D.
Medical University of Lodz, Lodz


 1 From Mouse to Man: Translational Value of Animal Models of Allergic Rhinitis 1 James G. Wagner and Jack R. Harkema

 2 Clinical Implications and Facts About Allergic Rhinitis (AR) in Children 17 Zorica Zivkovic, Sofija Cerovic, Ivana Djuric-Filipovic, Zoran Vukasinovic, Jasmina Jocic-Stojanovic and Aleksandra Bajec-Opancina

 3 The Impact of Allergic Rhinitis on Asthma: Current View 33 Betül Ayşe Sin

 4 Allergic Rhinitis and Its Impact on Bronchial Asthma 47 Katerina D. Samara, Stylianos G. Velegrakis and Alexander D. Karatzanis

 5 Clinical Variants of Allergic Rhinitis and Asthma Phenotypes in Patients with or Without a Smoking History 61 Sanja Popović-Grle

 6 Cough in Allergic Rhinitis 81 Renata Pecova and Milos Tatar

 7 Allergic Rhinitis and Its Impact on Sleep 107 J. Rimmer and J. Hellgren

 8 Allergic Rhinitis and Sports 119 Silva Diana, Moreira André and Delgado Luís

 9 Occupational Allergic Rhinitis in the Czech Republic – Situation in South Moravia Region 137 Petr Malenka

 10 Nasal Provocation Test in the Diagnosis of Allergic Rhinitis 153 Graça Loureiro, Beatriz Tavares, Daniel Machado and Celso Pereira

 11 Phototherapy for the Treatment of Allergic Rhinitis 183 Ko-Hsin Hu and Wen-Tyng Li

 12 Evaluation of Therapeutic Efficacy of Nigella sativa (Black Seed) for Treatment of Allergic Rhinitis 197 Abdulghani Mohamed Alsamarai, Mohamed Abdul Satar and Amina Hamed Ahmed Alobaidi .

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Published by: Unknown - Sunday, May 26, 2013


  1. Great resource on allergic rhinitis! Thanks for suggesting.