Open Access Medical Books


Edited by Miroslav Radenković .

392 pages . 
Open Access .

Gestational diabetes mellitus is generally defined as hyperglycemia with onset or first recognition during pregnancy. The incidence of gestational diabetes is still increasing and this pathological condition has strong association with adverse pregnancy outcomes. Given that gestational diabetes may have long-term pathological consequences for both mother and the child, it is important that it is promptly recognized and adequately managed. Preconceptional screening and medical informing of women with pre-existing diabetes, older age, family history of gestational diabetes, metabolic syndrome, obesity, polycystic ovary syndrome or hypertension would be significant in order to reduce the risk to the fetus and mother connected to gestational diabetes. Treatment of gestational diabetes is aimed to maintain euglycemia and it should involve regular glucose monitoring, dietary modifications, life style changes, exercise program, and when necessary, pharmacotherapy. In a longterm view, in order to prevent development of diabetes later in life, as well to avoid associated complications, an adequate education on lifestyle modifications should start in pregnancy and continue postpartum.
This book brings together 21 chapters of up-to-date information on gestational diabetes. The idea of this book is to direct the reader to comprehensively explore etiology and different aspects of prevention, screening, diagnosis, treatment, and postpartum follow-up in consideration to gestational diabetes. Furthermore, the presented facts provide a useful framework for both clinicians and basic investigators to further explore and update existing knowledge on diabetes related to pregnancy.
We hope that this book will be used as a reference textbook for researchers, medical specialists, teachers and students.
We express sincere appreciation to all the authors of the chapters for their enthusiasm and expertise.

Miroslav Radenković, MD, PhD
Associate Professor
Department of Pharmacology, Clinical Pharmacology and Toxicology
School of Medicine, University of Belgrade



 1 Novel Screening Approaches for the Early Detection of Gestational Diabetes Mellitus 1 Harry M. Georgiou, Sebastián Illanes López and Gregory E. Rice

 2 Gestational Diabetes Mellitus - A Perspective 21 Veerasamy Seshiah, Vijayam Balaji and Balaji Madhuri

 3 Gestational Diabetes: Evidence-Based Screening, Diagnosis and Treatment 41 Melania Maria Ramos Amorim and Leila Katz

 4 Validity of Fasting Blood Glucose Test in Screening for the Pre-Diabetes State Among Pregnant Females 61 Mostafa A Abolfotouh and Mohammed A Al-Rowaily

 5 Prevalence and Risk Factors for the Development of GD in Some Eastern European Countries – Tendencies and Pharmacoeconomical Assessment for the Choice of Treatment 69 Valentina Petkova and Irina Nikolova

 6 Pathophysiology of Gestational Diabetes Mellitus: The Past, the Present and the Future 91 Mohammed Chyad Al-Noaemi and Mohammed Helmy Faris Shalayel

 7 The Role of Adipocyte Mediators, Inflammatory Markers and Vitamin D in Gestational Diabetes 115 Sedigheh Soheilykhah

 8 Gestational Diabetes and the Metabolic Syndrome 141 Leanne R. De Souza, Joel G. Ray and Ravi Retnakaran

 9 Insulin Resistance in the Third Trimester of Pregnancy Suffering from Gestational Diabetes Mellitus or Impaired Glucose Tolerance 169 Mohammed Helmy Faris Shalayel, Mohammed Chyad Al-Noaemi and Salah A.M. Ahmed

 10 The Impact of Polycystic Ovarian Syndrome on Gestational Diabetes 183 Stefanie Aust and Johannes Ott

 11 Impact and Mechanisms of Pancreatic Beta-Cell Mass Programming by Maternal Diabetes - Insight from Animal Model Studies 201 Audrey Chavey, Jamileh Movassat and Bernard Portha

 12 Unravelling the Connection Between Gestational Diabetes Mellitus and Butyrylcholinesterase 227 Alexander E. Omu Frcog

 13 Gestational Hyperglycemia, Excessive Pregnancy Weight Gain and Risk of Fetal Overgrowth 243 Xinhua Chen, Theresa O. Scholl, Robert A. Steer and T. Peter Stein

14 Congenital Cardiopathies Screening Associated with Diabetes Mellitus Using Maternal Fructosamine Plasma Concentration 255 Zilma Silveira Nogueira Reis and Gabriel Costa Osanan

 15 Applications of Doppler Studies for Fetal Surveillance in Diabetic Pregnancies 263 William WK To

 16 The Influence of Diet to Control the Metabolism in Gestational Diabetes Mellitus 277 Rebeca Monroy-Torres and Jaime Naves-Sanchez

 17 Insulin Use in Gestational Diabetes – Pragmatic Protocols for Self-Management and for Labour and Delivery 293 Sara J Meltzer and Rima Alsayari

 18 Treatment Considerations for Gestational Diabetes Mellitus and Long-Term Postpartum Options 315 Miroslav Radenković

 19 Glyburide Disposition During Pregnancy 325 Diana L. Shuster, Mary F. Hebert and Qingcheng Mao

 20 Exercise Guidelines for Women with Gestational Diabetes 339 Michelle F. Mottola and Stephanie-May Ruchat

 21 Gestational Diabetes Mellitus After Delivery 363 Aleida M. Rivas

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Published by: younes younes - Saturday, May 4, 2013


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