Open Access Medical Books

TEXTBOOK : STEROIDS – BASIC SCIENCE

STEROIDS

Edited by Hassan Abduljabbar .

244 pages .
Open Access .

This book explains the basic science of steroids and is targeted towards professionals engaged in health services.
It should be noted that medical science evolves rapidly and some information like the understanding of steroids and their therapeutic use may change with new concepts quickly.
Steroids are either naturally occurring or synthetic fat-soluble organic compounds. They are found in plants, animals, and fungi. They mediate a very diverse set of biological responses. The most widespread steroid in the body is cholesterol, an essential component of cell membranes, and the starting point for the synthesis of other steroids.
Since the science of steroids has an enormous scope, we decided to put the clinical aspects of steroids in a different book titled “Steroids: Clinical Aspects”. The two books complete each other.
We hope that the reader will gain valuable information from both books and enrich their knowledge about this fascinating topic.

Hassan Abduljabbar
Professor of Obstetrics and Gynecology,
King Abdulaziz University,
Kingdom of Saudi Arabia 
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CONTENTS : 



Part 1 Physiology of Steroid Hormones .


 1 Hormonal and Neural Mechanisms Regulating Hormone Steroids Secretion 3 Roberto Domínguez, Angélica Flores and Sara E. Cruz-Morales

 2 The Tissue Specific Role of Estrogen and Progesterone in Human Endometrium and Mammary Gland 35 Karin Tamm, Marina Suhorutshenko, Miia Rõõm, Jaak Simm and Madis Metsis

3 Evolving Trends in Estrogen Receptor Biology 65 Raghava Varman Thampan

Part 2 Pathophysiology of Steroid Hormones .


 4 Cryptorchidism and Steroid Hormones 85 Marzena Kamieniczna, Anna Havrylyuk and Maciej Kurpisz

 5 Dehydroepiandrosterone in Nonalcoholic Fatty Liver Disease 97 Yoshio Sumida, Kyoko Sakai, Tomoyuki Ohno, Kazuyuki Kanemasa, Yutaka Inada, Naohisa Yoshida, Kohichiroh Yasui, Yoshito Itoh, Yuji Naito, Toshikazu Yoshikawa

 6 DHEA and Impaired Glucose Tolerance Clinical and Basic Study 109 Hajime Ueshiba

 7 17-Hydroxysteroid Dehydrogenase Type 3 Deficiency: Diagnosis, Phenotypic Variability and Molecular Findings 119 Maria Felicia Faienza and Luciano Cavallo

 8 Steroid Hormones in Drosophila: How Ecdysone Coordinates Developmental Signalling with Cell Growth and Division 141 Leonie Quinn, Jane Lin, Nicola Cranna, Jue Er Amanda Lee, Naomi Mitchell and Ross Hannan

Part 3 Pharmacology .


 9 Approaches for Searching of Modified Steroid Estrogen Analogues with Improved Biological Properties 171 Alexander Shavva, Svetlana Morozkina and Olga Galkina

 10 Drug Design Approaches to Manipulate the Agonist-Antagonist Equilibrium in Steroid Receptors 221 Scott J. Lusher, Paolo Conti, Wim Dokter, Pedro H. Hermkens and Jacob de Vlieg




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