Open Access Medical Books

TEXTBOOK : AGE-RELATED MACULAR DEGENERATION - ETIOLOGY, DIAGNOSIS AND MANAGEMENT - A GLANCE AT THE FUTURE

MACULAR DEGENERATION

Edited by Giuseppe Lo Giudice .

Open Access .
200 pages .
ISBN 978-953-51-1113-9 .

Management of the patient affected by age-related macular degeneration (AMD) represents a paradigm challenge. Research has yielded major discoveries about the etiology, pathophysiology, and treatment of AMD over the last decade, although more steps are needed to continue to improve our know-how. The purpose of "Age-related Macular Degeneration - Etiology, Diagnosis and Management - A Glance at the Future" is to provide up-to-date information of the pathophysiology, diagnosis, management, and treatment of age-related macular degeneration. In this volume I have attempted to collect a significant amount of new information from retinal experts to first summarize the established information and then to present the most novel developments in their respective fields. The first section of this book includes the pathophysiology and epidemiology, of agerelated macular degeneration. Oxidative damage to the RPE, extracellular matrix turnover, inflammation, and angiogenesis appear to be key cellular processes that play a central role in the pathogenesis of AMD. Some chapters will focus on the pathobiology of early stage AMD and its evolution to the later form also exploring the role of injury at the RPE in the onset and development of the disease. The second section focuses on the clinical features and diagnosis of age-related macular degeneration. The clinical findings seen in the nonexudative and exudative forms are discussed.
The section on imaging includes a chapter on new OCT technology including: Swept Source OCT (SS-OCT), Enhanced Depth Imaging OCT (EDI-OCT), and adaptive optics. A variety of emerging OCT technologies are poised to expand significantly the scope of OCT imaging and to enhance significantly our approach to the diagnosis and management of patients with retinal disease.
An in-depth understanding of these technologies and their potential advantages and disadvantages will aid retinal specialists in utilizing these new methods optimally. The next and last section reports information on current and experimental forms of treatment for non-exudative and exudative forms of age-related macular degeneration.
The advent of intravitreal anti-VEGF therapy (targeting all isoforms) dramatically altered the standard of care and treatment paradigms for patients with NVAMD. However, In spite of this significant step forward in the treatment of NVAMD, significant challenges remain. The presentation of the treatment options includes a discussion of the mechanism of action, the clinical treatment technique, the targeted patient population, as well as the expected outcomes of each treatment. No single manageable volume can analyze all of the existing knowledge concerning a disease such as age-related macular degeneration. Special attention has been paid to making the text easily readable. My sincere hope is that readers will find as much pleasure reading this textbook as I have had writing and editing it.

Dr. Giuseppe Lo Giudice
San Paolo Ophthalimc Center, San Antonio Hospital, 
Italy
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CONTENTS : 

Section 1 Epidemiology and Risk Factors of Age- Related Macular Degeneration .


 1 AMD: Epidemiology and Risk Factors 3 Jane Khan

 2 Cigarette Smoking and Hypertension Two Risk Factors for Age- Related Macular Degeneration 39 Maria E. Marin-Castaño

Section 2 Classification, Clinical Features and New Advance in Optical Coherence Tomography Diagnosis .


 3 Classification and Clinical Features of AMD 105 Petr Kolar

 4 New Insights into the Optical Coherence Tomography – Assessement and Follow-Up of Age-Related Macular Degeneration 133 Simona-Delia Ţălu

Section 3 New Trend in the Management of Age- Related Macular Degeneration .


 5 Anti VEGF Agents for Age Related Macular Degeneration 163 Shani Golan, Michaella Goldstein and Anat Loewenstein .



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Published by: younes younes - Thursday, June 13, 2013

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