Open Access Medical Books

TEXTBOOK : AMYLOIDOSIS

AMYLOIDOSIS

Edited by Dali Feng .

248 pages .
Open Access .
ISBN 978-953-51-1100-9 .

Amyloidosis is an uncommon disorder characterized by the deposition of extracellular fibril amyloid proteins in various organs and tissues. It is estimated that there are about 3,000 new cases annually in the United States. Amyloidosis is classified by the precursor plasma proteins that form the extracellular fibril deposits. The primary systemic type, or the AL type, is due to monoclonal immunoglobulin free light chains. The hereditary type, also known as familial type, is mostly secondary to mutant transthyretin deposition while the wild type transthyretin type or also called senile type is due to normal wild-type transthyretin deposition. The secondary type or the AA type is related to amyloid A protein, which is an acute reactive protein.
Dialysis related amyloidosis is caused by the deposition of β2-microglobulin, which has been increasingly recognized. Significant advancement has been made recently, which not only provides insight into its pathophysiology but also helps to discover new therapies to fight the deadly disease.
Unfortunately, because of rarity of the disease and its protean clinical manifestations, many patients were misdiagnosed, especially at early stage of the disease. Consequently, many patients missed the opportunity window of effective therapy, in particularly the AL type. The aim of the book is to review the fascinating history and the mechanism of the disease; to help the readers become familiar with the clinical presentation; and to review the latest diagnostic and therapeutic development. Effective or even curative therapies are available, especially if accurate diagnosis and typing are made early.
I would like to thank all the authors who have contributed to the book and congratulate them on their excellent works. This volume provides a comprehensive update of our knowledge on amyloidosis of different types. It will be a useful daily reference for physician and other health care providers who take care of amyloid patients.
I would like to sincerely thank my parent and my family (Gloria, Amy, Emily and Eric) for their endless love and support. You spent more time waiting for me than being with me while I was studying, writing, and taking care of my patients. I would also like to thank my several mentors, including Drs. Liu Lisheng, Zhu Guoying, Geoffrey Toffler, James Muller, Joseph Loscalzo, Jae Oh, Rick Nishimura, Carole Warnes and Kyle Klarich. You continue to inspire me to become a better cardiologist and a better person. Finally, I greatly appreciate Dr. Cynthia Taub for her insightful suggestion, contribution and inspiration on the book.

Dali Feng, MD, FACC.
The Metropolitan Heart and Vascular Institute
Minneapolis, Minnesota , USA
-->

CONTENTS : 

Section 1 of the Textbook : History and Clinical Diagnosis and Typing of Amyloidosis .


 1 Title: “Amyloid” — Historical Aspects 3 Maarit Tanskanen

 2 Diagnosis of Amyloidosis 25 Cezar Augusto Muniz Caldas and Jozélio Freire de Carvalho

 3 Cardiac Amyloidosis: Typing, Diagnosis, Prognosis and Management 33 Glenn K. Lee, DaLi Feng, Martha Grogan, Cynthia Taub, Angela Dispenzieri and Kyle W. Klarich

 4 Dialysis-Related Amyloidosis: Pathogenesis and Clinical Features in Patients Undergoing Dialysis Treatment 67 Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama and Ichiei Narita

 5 Ocular Presentations of Amyloidosis 85 Hesam Hashemian, Mahmoud Jabbarvand, Mehdi Khodaparast, Elias Khalilipour and Hamid Riazi Esfehani

Section 2 of the Textbook : Amyloidosis -The Mechanism of the Disease .


 6 Transthyretin-Related Amyloidoses: A Structural and Thermodynamic Approach 113 Estefania Azevedo, Priscila F. Silva, Fernando Palhano, Carolina A. Braga and Debora Foguel

 7 Anti-Cytokine Therapy for AA Amyloidosis 131 Keisuke Hagihara, Syota Kagawa, Yuki Kishida and Junsuke Arimitsu

Section 3 of the Textbook : Amyloidosis The Advancement of Therapy .


 8 Treatment of End Stage Heart Failure Related to Cardiac Amyloidosis 155 Tal Hasin, Eugenia Raichlin, Angela Dispenzieri and Sudhir Kushwaha

 9 Diagnosis and Treatment of AA Amyloidosis with Rheumatoid Arthritis: State of the Art 187 Takeshi Kuroda, Yoko Wada and Masaaki Nakano

 10 Therapeutic Strategies in Amyloid A Amyloidosis Secondary to Rheumatoid Arthritis 213 Tadashi Nakamura .



You've just read an article category Endocrinology and Metabolism by title TEXTBOOK : AMYLOIDOSIS. You can bookmark this page URL http://www.openaccessbooks.com/2013/06/textbook-amyloidosis.html. Thank you!
Published by: younes younes - Thursday, June 13, 2013

No comments yet "TEXTBOOK : AMYLOIDOSIS"

Post a Comment