Open Access Medical Books

TEXTBOOK : CHALLENGES IN RHEUMATOLOGY

RHEUMATOLOGY

Edited by Miroslav Harjacek .

202 pages .
Open Access .
ISBN 978-953-307-848-9

Challenges in Rheumatology aims to provide a general review for those who need quick up-to-date information on various aspects and impacts of rheumatic diseases.
Rheumatology is a subspecialty of medicine that focuses on the biology, cause, diagnosis and treatment of a variety of musculoskeletal and other systemic diseases.
Rheumatic diseases can present themselves in a number of familiar ways but sometimes are atypical and occasionally puzzling. Patients may appear insidiously or acutely ill and the impact of the disease can range from a temporary irritation, to a condition that is persistent and increasingly disabling, and sometimes a severe, even life-threatening illness. Most clinicians have a basic understanding of common disorders, yet they are often challenged by specific questions regarding the optimal diagnosis and care for patients with rheumatic diseases. More than ever, the care for patients with rheumatic diseases requires a multidisciplinary approach. In addition, the magic of the Internet has allowed our patients to be far better informed about their own health issues. They are demanding, and have the right to be active participants and decision-makers in their own care. If we are to act as their educators and advisors, we must continually strive to expand our own knowledge base.
The field of rheumatology is expanding rapidly and several very exciting developments have occurred in recent years. Firstly, there has been a dramatic shift in our understanding of the nature of inflammation and the possibility of specifically regulating the aberrant immune inflammatory response. Secondly, an understanding of the pathogenesis has lead to the development of new, more targeted therapies. As a practicing pediatric rheumatologist, I have always enjoyed treating the broad range of conditions that challenge my diagnostic skills and treatment abilities on a daily basis.
Early in my career, treatment options were far more limited than today, but with the development of biologic therapies, primarily anti-tumor necrosis factor alpha (TNF-α), and others as well, therapeutic success has consequently increased significantly. That development has clearly changed the lives of many of our patients and revitalized an entire generation of rheumatologists.
Challenges in Rheumatology has assembled an impressive group of international experts who have studied specific aspects of certain rheumatic diseases and have extensive experience either in pathophysiology or an in-depth diagnosis and/or management of rheumatic patients. They communicate their knowledge and experience to the reader in chapters that are conveniently organized as pathophysiology, clinical manifestations and diagnosis of selected rheumatic diseases, medical and perioperative orthopedic management, and the economic impact of rheumatic diseases.
I am extremely grateful to the many authors who contributed to this book. I too, have learned a lot on various aspects of experimental and clinical rheumatology form editing the text. My hope is that this book will help our trainees become better physicians and scientists, and practicing rheumatologists to provide better care, and ultimately, improve the quality of life of our patients.

Prof. Dr. Miroslav Harjacek MD, PhD,
Children's Hospital Srebrnjak,
Department of Pediatric and Adolescent Rheumatology,
University of Zagreb, School of Medicine,
Croatia
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CONTENTS : 

Part 1 of  the Textbook : Economic Impact of Rheumatic Diseases .


 1 Economic Impact of Rheumatic Diseases 3 Gerardo Quintana L. and Paola Coral-Alvarado

 2 Economic Evaluations in Systemic Lupus Erythematosus 13 Gerardo Quintana, Helena Avella Bolivar and Paola Coral-Alvarado

Part 2 of  the Textbook : Etiopathogenesis of Rheumatic Diseases .


 3 Role of Bone Marrow in the Pathogenesis of Rheumatoid Arthritis 27 Shunsei Hirohata

 4 Estrogens Involvement in the Physiopathology of Articular Cartilage 41 Moslemi Safa, Demoor Magali, Boumediene Karim, Galera Philippe and Maneix Laure

Part 3 of  the Textbook : Clinical Manifestations and Diagnosis of Rheumatic Diseases .


 5 Rheumatoid Arthritis Interstitial Lung Disease 65 Ophir Vinik, Theodore Marras, Shane Shapera and Shikha Mittoo

 6 Juvenile Spondyloarthritis 89 Miroslav Harjaček, Lovro Lamot, Lana Tambić Bukovac, Mandica Vidović and Rik Joos

 7 Ultrasonography in Diagnosis and Follow-Up of Temporal Arteritis: An Update 129 Giovanni Ciancio, Marco Bruschi and Marcello Govoni

Part 4 of  the Textbook : Management and Therapy of Rheumatic Diseases .


 8 Perioperative Management of Non-Biological and Biological Therapies in Rheumatic Patients Undergoing Orthopedic Surgery 145 Juan Salvatierra Ossorio, Magdalena Peregrina-Palomares, Francisco O´Valle Ravassa and Pedro Hernandez-Cortes

 9 Optimal Treatment Strategy for Amyloid A Amyloidosis in Rheumatic Diseases – Anti Interleukin-6 Receptor Therapy 155 Yasuaki Okuda

 10 Integral Treatment of Systemic Lupus Erythematosus 169 Raquel Ramírez Parrondo




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