Open Access Medical Books

Hepatocellular Carcinoma - Future Outlook

Hepatocellular Carcinoma - Future Outlook

Edited by Ahmed O. Kaseb .

ISBN 978-953-51-1202-0 .
322 pages .
Open Access .

Hepatocellular carcinoma (HCC) develops as a consequence of underlying chronic liver disease, most commonly cirrhosis. Therefore, HCC management draws on the expertise of a range of medical specialists. Many components of current novel therapeutic modalities for HCC are discussed in the current version of the book within the framework of a multidisciplinary approach with special emphasis on emerging treatment approaches and research strategies. This book is the essential clinical guide for oncologists, hepatologists, surgeons, and all physicians and researchers involved in the care of patients with HCC. I would like to thank the authors for their significant efforts in bringing this edition to life. This book is a tribute to their continued dedication to improving HCC outcome.

Dr. Ahmed Kaseb
University of Texas M.D. Anderson Cancer Center .


 1 Role of Alleles and Genotypes of Polymorphisms of IL-18 (-607 C/A; and -137 C/G), IFN-γ (+874 A/T) and TNF-α (-238 A/G and -308 A/G) and HLA-G Genes in the Susceptibility of Hepatocellular Carcinoma. by Andreza Correa Teixeira, Ana de Lourdes Candolo Martinelli and Eduardo Antonio Donadi

 2 Liver Transplantation for Hepatocellular Carcinoma . by Emad H. Asham, Howard Mansour and Mark Ghobrial

 3 Radioembolization for the Treatment of Unresectable Hepatocellular Carcinoma . by Hojjat Ahmadzadehfar, Amir Sabet and Hans Jürgen Biersack

 4 Image-Guided Therapies for Hepatocellular Carcinoma in Hepatocelluar Carcinoma — Future Outlook . by Bruno C. Odisio, Ravi Murthy and Michael J. Wallace

 5 Neoadjuvant Chemotherapy for Hepatocellular Carcinoma . by Xin-yu Huang, Qi Zheng and Zhou Yuan

 6 Targets and Approaches to Control Hepatocellular Carcinoma in Future . by Mukherjee Biswajit, Hossain Chowdhury Mobaswar , Bhattacharya Sanchari and Shampa Ghosh

 7 Early Chronic Inflammation and Subsequent Somatic Mutations Shift Phospho-Smad3 Signaling from Tumor- Suppression to Fibro-Carcinogenesis in Human Chronic Liver Diseases . by Miki Murata, Katsunori Yoshida and Koichi Matsuzaki

 8 Surgical Treatment Strategies and Prognosis of Hepatocellular Carcinoma . by Alessandro Uzzau, Maria Laura Pertoldeo, Vittorio Cherchi, Serena Bertozzi, Claudio Avellini and Giorgio Soardo

 9 Conditions that Predispose to the Development of HCC: The Role of Tumor Associated Fibroblasts and of microRNA . by C. Avellini, D. Cesselli, A.P. Beltrami, M. Orsaria, S. Marzinotto, F. Morassi and S. Uzzau

 10 Signs and Symptoms of HCC . by Valerio Barghini, Debora Donnini, Alessandro Uzzau and Giorgio Soardo

 11 Sorafenib in the Continuum of Care for Hepatocellular Carcinoma: Challenges in Defining Optimal Practice . by Ahmed O. Kaseb and Laura M. Kulik

 12 Sorafenib-Inhibited Signaling: Emerging Evidence of RAFIndependent Pathways as Potential Therapeutic Targets in Hepatocellular Carcinoma . by Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa and Shun Fujimaki

 13 Insulin-Like Growth Factor-II: Molecular-Targeted Therapy for Hepatocellular Carcinoma . by Min Yao, Li Wang, Meijuan Yan, Xiaodi Yan and Dengfu Yao

 14 Simultaneous Changes in Expression of Bile Canalicular CD10 and Sinusoidal CD105 (Endoglin) in Chronic Hepatitis and Liver Cirrhosis . by Toshitsugu Nakamura

 15 Hepatocellular Carcinoma, Steroid Hormones and Metalloproteases . by Noemí Eiró, Belen Fernandez-Garcia, Antonio Altadill, Luis O. González and Francisco J. Vizoso .

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Published by: Unknown - Wednesday, August 24, 2016

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